Role of ET-1, Physical Activity, and Sedentary Behavior in Microvascular Dysfunction Following GDM

Recruiting Early Phase 1 Interventional Study
Gestational Diabetes Endothelial Dysfunction Physical Inactivity
Healthy Volunteers Welcome You do not need to have the condition being studied to take part.
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Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 – 50
Sex
Female
Trial phase
Early Phase 1
Study type
Interventional
Purpose
Basic Science
Participants needed
40 (estimated)
Sponsor
Anna Stanhewicz, PhD · Other
Who this trial is looking for

This trial is looking for women who have been pregnant in the last five years, especially those who had gestational diabetes. They should be generally healthy, but won't be able to participate if they have certain health issues like high blood pressure, liver problems, or if they're currently smoking or pregnant. It's also important that they don’t have very low body weight or any allergies to things used during the study.

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About This Trial
Women with a history of gestational diabetes mellitus (GDM) are at a 2-fold greater risk for the development of overt cardiovascular disease (CVD) following the effected pregnancy. While subsequent development of type II diabetes elevates this risk, prior GDM is an independent risk factor for CVD morbidity, particularly, within the first decade postpartum. GDM is associated with impaired endotheli…
Trial Locations
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Eligibility Criteria
INCLUSION CRITERIA * history of pregnancy within 5 years of the study visit * had healthy pregnancy OR had gestational diabetes diagnosed by their obstetrician and confirmed according to the American College of Obstetricians and Gynecologists criteria for gestational diabetes. EXCLUSION CRITERIA …
Contacts

Anna Reid-Stanhewicz, PHD

319-467-1732

anna-stanhewicz@uiowa.edu

CONTACT