Time Restricted Eating for Alzheimer's Disease
TREAD: Time Restricted Eating Intervention for Alzheimer's Disease
Recruiting
Phase 1
Interventional Study
Mild Cognitive Impairment
Alzheimer Disease
Alzheimer's Disease
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 60 and older
- Sex
- Any
- Trial phase
- Phase 1
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 60 (estimated)
- Sponsor
- University of California, San Diego · Other
Who this trial is looking for
This trial is looking for older adults with Mild Cognitive Impairment or early to moderate Alzheimer's Disease. Participants will follow a diet that involves fasting for 14 hours each night for 3 to 6 months and will visit the clinic for check-ups and tests during that time.
Are You a Good Fit for This Trial?
You may be able to join if
- I am 60 years or older.
- I have been diagnosed with Mild Cognitive Impairment or Alzheimer's Disease.
- I am in good health according to my medical history.
- I can complete cognitive tests and provide blood samples.
- I usually fast for less than 12 hours each night.
- I have a partner who is cognitively normal and scores above 26 on the MoCA test.
You may not be able to join if
- I have another neurodegenerative condition.
- I have cognitive impairment not related to Alzheimer's Disease.
- I have been diagnosed with diabetes.
- I have used insulin in the past 6 months.
- I started a new medication for MCI or Alzheimer's Disease in the last 3 months.
- I take any medication that affects appetite.
- I have a history of disordered eating.
- I am currently working shifts.
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
Check Your Eligibility
About This Trial
The goal of this clinical trial is to learn if restricting the time of eating to allow for prolonged fasting at night may reduce sleep disturbances, cognitive decay, and pathology in patients diagnosed with Mild Cognitive Impairment (MCI) or early to moderate Alzheimer's disease (AD). It will also learn about the feasibility of practicing 14 h of nightly fasting in this group of older adults. The …
Trial Locations
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Eligibility Criteria
Provision of signed and dated informed consent form. Stated willingness to comply with all study procedures and availability for the duration of the study.
Inclusion criteria
1. Persons, aged ≥60 years
2. In good general health as evidenced by medical history or diagnosed with clinical diagnosis o…
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