Accelerated TMS Treatment for Depression

fMRI Accelerated TMS Depression

Recruiting Observational Study
Depression
No Placebo Group Every participant receives an active treatment — no one gets a placebo. No Study Drug Researchers observe your health over time — no experimental treatment is given.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 – 65
Sex
Any
Study type
Observational
Participants needed
20 (estimated)
Sponsor
Medical University of South Carolina · Other
Who this trial is looking for

This trial is looking for adults with depression who want to try a new brain treatment. Participants will undergo brain scans and an accelerated treatment with transcranial magnetic stimulation (TMS) to see how their brain responds.

Are You a Good Fit for This Trial?
Rules you out Cortisol medication useElectroconvulsive therapySevere headachesAlcohol use disorderSubstance use disorderPregnancy

You may be able to join if

  • I am between 18 and 65 years old.
  • I can provide my own consent and understand English.
  • I have been diagnosed with major depressive disorder.

You may not be able to join if

  • I cannot speak English.
  • I have conditions that make it unsafe for me to have an MRI.
  • I have untreated medical, neurological, or psychiatric conditions.
  • I have metal implants in my head, heart, or neck.
  • I have had brain surgery in the past.
  • I have used cortisol medications or had electroconvulsive therapy.
  • I have other psychiatric or neurological illnesses.
  • I have a personal history of serious head injuries.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.

Check Your Eligibility
About This Trial

This study aims to investigate whether phenotypic-related brain states revealed by a novel INSCAPE ("Individualized Network-based Single-frame Coactivation Pattern Estimation") neuroimaging method in Major Depressive Disorder (MDD) patients can track brain recovery of MDD patients over an accelerated antidepressant transcranial magnetic stimulation (TMS) treatment.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Age 18-65 * Have the capacity and ability to provide one's own consent in English and sign the informed consent document. * DSM-IV diagnosis of MDD Exclusion Criteria: * Unable to speak English. * Contraindicated for MRI. * Any current or recent untreated medical, neurologic…
Contacts

Marion Wood

843-792-9502

woodma@musc.edu

CONTACT