Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
45 (estimated)
Sponsor
Mayo Clinic · Other
Who this trial is looking for
This trial is looking for people with Long COVID who want to help researchers understand how certain breathing conditions affect their brain function. Participants will be tested for their ability to handle low and high oxygen levels.
Are You a Good Fit for This Trial?
Rules you outChronic kidney diseaseChronic liver disease
You may be able to join if
I speak English
I have been diagnosed with Long COVID
You may not be able to join if
I have a history of coronary artery or aortic dissection
I have a neurological disease like dementia or Alzheimer's
I have had a stroke or cerebrovascular disease
I have an aneurysm
I have moderate to severe chronic obstructive pulmonary disease
I have uncontrolled moderate to severe asthma
I have moderate to severe bronchiectasis
I have moderate to severe lung disease that needs supplemental oxygen
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
This study aims to assess the effects of both acute and chronic exposures to hypoxia and hypercapnia in patients with Long COVID syndrome.
Trial Locations
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City
State
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Status
Eligibility Criteria
Inclusion criteria:
* English speaking
* Diagnosis of Long COVID
Exclusion criteria:
* Any history of:
* Coronary artery dissection or aortic dissection
* Neurological disease (e.g. dementia, Alzheimer's disease, or other brain-related disease)
* Cerebrovascular disease or stroke
* Aneur…
Inclusion criteria:
* English speaking
* Diagnosis of Long COVID
Exclusion criteria:
* Any history of:
* Coronary artery dissection or aortic dissection
* Neurological disease (e.g. dementia, Alzheimer's disease, or other brain-related disease)
* Cerebrovascular disease or stroke
* Aneurysm
* If currently has:
* Moderate-severe chronic obstructive pulmonary disease
* Uncontrolled moderate-severe asthma
* Moderate-severe bronchiectasis
* Moderate-severe interstitial lung disease, requiring the use of supplemental oxygen
* A necessity to use supplemental oxygen, for any reason
* New or worsening symptoms (decompensation) of heart failure
* Right heart disease due to chronic pulmonary disease/sleep apnea
* Uncontrolled myocardial ischemia or angina
* Uncontrolled heart arrhythmias
* Heart or lung infection (e.g. myocarditis or pericarditis)
* Left main coronary artery stenosis
* Moderate-severe aortic stenosis
* Pulmonary embolism, pulmonary infarction, or other blood clots
* Severe respiratory disease
* Chronic kidney disease
* Chronic liver disease
* Females of childbearing potential will complete a urine pregnancy test at their baseline visit to rule out pregnancy
* BMI \>40
* Study staff unable to obtain adequate signal for cerebral blood flow
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