No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 – 45
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
160 (estimated)
Sponsor
University of Washington · Other
Who this trial is looking for
This trial is looking for adults aged 18-45 who are seeking treatment for social anxiety disorder or body dysmorphic disorder. Participants will share information that may help researchers learn why some people benefit from cognitive behavioral therapy while others do not.
I have social anxiety disorder or body dysmorphic disorder
I speak English fluently
I am seeking treatment for my condition
You may not be able to join if
I score below 80 on the WRAT5 Word Reading Subtest
I have current suicidal or homicidal thoughts
I have a history of manic or hypomanic episodes
I have current substance use issues in the past 6 months
I am currently taking psychotropic medications, except stable antidepressants
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
The purpose of this study is to understand why some individuals respond fully to cognitive behavioral therapy and others do not, based on multiple sources of data such as neural, neurocognitive, clinical, and self-report data.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
Clinical sample (N=110):
1. Men and women, age 18-45
2. Treatment-seeking individuals who meet criteria for a primary DSM-5 diagnosis of primary social anxiety disorder (SAD) or body dysmorphic disorder (BDD) based on the SCID-5-RV
3. Fluent in English and willing to provide in…
Inclusion Criteria:
Clinical sample (N=110):
1. Men and women, age 18-45
2. Treatment-seeking individuals who meet criteria for a primary DSM-5 diagnosis of primary social anxiety disorder (SAD) or body dysmorphic disorder (BDD) based on the SCID-5-RV
3. Fluent in English and willing to provide informed consent.
Control sample (N=50):
1. Men and women, age 18-45
2. No current or lifetime history of psychiatric disorders, as assessed using the SCID-5-RV
3. Meet criteria for low levels of anxiety (GAD-7 score of \<8) and depression (PHQ-9 score \<10)
4. Fluent in English and willing to provide informed consent
Exclusion Criteria:
All groups:
1. Score \< 80 based on WRAT5 Word Reading Subtest
2. fMRI contraindications (e.g., electronic medical devices such as pacemakers, implanted defibrillators, etc.; metal implants not approved for MRI; pregnancy; claustrophobia)
2\. Active suicidal or homicidal ideation, or any features requiring a higher level of care 3. Lifetime history of manic or hypomanic episode, psychotic symptoms, traumatic brain injury, neurological disorder, pervasive developmental disorder, or attention deficit-hyperactivity disorder; active alcohol or substance use disorder in the past 6 months 4. Current use of psychotropic medications, except antidepressants taken at a stable dose for 3 months prior to study baseline 5. Previous CBT non-responder or current CBT
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