Obesity and Hormone Response Study in Women
Convergent Mechanisms Underlying Reprometabolic Syndrome in Women
- Age
- 18 – 38
- Sex
- Female
- Trial phase
- Phase 2
- Study type
- Interventional
- Purpose
- Basic Science
- Participants needed
- 20 (estimated)
- Sponsor
- University of Colorado, Denver · Other
This trial is looking for women aged 18-38 who have regular menstrual cycles and are not using reproductive hormones. Participants will take part in research to understand how obesity affects hormone responses related to fertility.
You may be able to join if
- I am aged 18-38
- I have regular menstrual cycles every 25-35 days
- I have not used reproductive hormones in the past 3 months
- I have not taken medications that affect reproductive hormones
- I agree to use reliable barrier contraception or abstain from intercourse
- My thyroid stimulating hormone, prolactin, and lipid profiles are normal
- I exercise moderately for no more than 4 hours a week
- I have no history of chronic diseases affecting reproductive hormones
You may not be able to join if
- I have diabetes
- I smoke
- I have a history of blood clots or known blood clotting disorders
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
Check Your EligibilityDr. Nanette Santoro proposes to test the specific question that obesity results in abnormal estradiol response at the level of the pituitary and hypothalamus. This will be shown in diminished pituitary sensitivity to gonadorelin releasing hormone with a reduced estradiol induced luteinizing hormone surge in obese women.
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