No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 – 30
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
45 (estimated)
Sponsor
University of North Carolina, Chapel Hill · Other
Who this trial is looking for
This trial is looking for young adults with mild to moderate depression. Participants will attend a session where they will receive therapy or information about coping with depression, and their brain activity will be measured during the session.
Are You a Good Fit for This Trial?
You may be able to join if
I am between 18 and 30 years old
I am a full-time student
I have mild to moderate depression symptoms
I can understand the study procedures
I can speak and understand English
I am willing to follow study procedures
You may not be able to join if
I have had current suicidal thoughts in the past month
I have attempted suicide at any time in my life
I started therapy in the past month
I am at high risk for psychosis
I have been diagnosed with autism spectrum disorder
I take more than 20 mg of diazepam daily
I cannot give informed consent to participate
I cannot effectively communicate in English
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
The goal of this study is to learn the extent to which client-therapist brain activity may synchronize during a psychosocial intervention for depression symptoms.
The study will compare behavioral activation, a client-centered type of cognitive-behavioral therapy, to psychoeducation which delivers information on strategies to recover from depression symptoms.
Participants will answer questions a…
The goal of this study is to learn the extent to which client-therapist brain activity may synchronize during a psychosocial intervention for depression symptoms.
The study will compare behavioral activation, a client-centered type of cognitive-behavioral therapy, to psychoeducation which delivers information on strategies to recover from depression symptoms.
Participants will answer questions about their mental and physical health, attend one psychosocial intervention session receiving either Behavioral Activation or Psychoeducation with simultaneous brain activity measurement and complete follow up surveys two weeks and one month following the intervention.
Trial Locations
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Eligibility Criteria
Inclusion Criteria for participants/clients:
* Between ages 18 and 30
* Full-time student status (undergraduate, graduate, and professional)
* Experience mild to moderate depressive symptoms as determined by the Beck Depression Inventory (score: 14-28)
* Capacity to understand study procedures (inf…
Inclusion Criteria for participants/clients:
* Between ages 18 and 30
* Full-time student status (undergraduate, graduate, and professional)
* Experience mild to moderate depressive symptoms as determined by the Beck Depression Inventory (score: 14-28)
* Capacity to understand study procedures (informed consent)
* Ability to speak and understand English
* Willingness to comply with study procedures
Inclusion Criteria for therapists:
* Ages 18 or older
* Qualification to administer therapy (decided by the Principal Investigator)
* Capacity to understand the study procedures (informed consent)
* Speak and understand English
* Willingness to comply with study procedures
Exclusion Criteria for participants/clients:
* Active, Current Suicidal ideation as determined by the Columbia-Suicide Severity Rating Scale (C-SSRS) in the past month
* Past suicidal attempt (lifetime)
* Recently initiated psychotherapy (past month)
* Elevated psychosis risk based on self-report prodromal questionnaire - brief version (PQ-B) or self-reported diagnosis of psychotic disorder by mental health provider
* Positive screen for autism spectrum disorder based on the self-report autism quotient (AQ-10) or self-reported diagnosis of autism spectrum disorder by mental health provider,
* Daily intake of benzodiazepine of \>20 mg diazepam milligram equivalent
* Inability to give informed, voluntary, written consent to participate
* Inability to effectively communicate in English as determined by interaction with study personnel
* Anything else that in the assessment of the study team is not conducive to the successful completion of the study requirements.
There are no exclusion criteria for therapists
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