Positive Affect Intervention for Depression in HIV Patients
Project neuroARTEMIS
Recruiting
N/A
Interventional Study
Stimulant Use
Human Immunodeficiency Virus (HIV)
Depression
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 – 59
- Sex
- Any
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 189 (estimated)
- Sponsor
- Wake Forest University Health Sciences · Other
Who this trial is looking for
This trial is looking for people who are HIV positive and use stimulants. Participants will help researchers understand how stress affects mood and behavior, with the hope of finding better treatments for depression and substance use.
Are You a Good Fit for This Trial?
You may be able to join if
- I am between 18 and 59 years old
- I use stimulants weekly or have a score of 4 or more on the ASSIST test
- I have a confirmed HIV diagnosis
- I am currently taking daily oral antiretroviral therapy
- I can speak and read English
You may not be able to join if
- I have an acute brain infection
- I have an acutely symptomatic bipolar I or psychotic disorder
- I am prescribed immunomodulatory medications or immunotherapy
- I have a condition that makes me unsuitable for an MRI
- I have been taking antidepressant medication for at least 2 months
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
Check Your Eligibility
About This Trial
The purpose of this research is to understand how chronic stress affects the way our brain and immune systems function, and in turn how this affects the way people feel, think, and behave. By learning more about how these processes work, the hope is to be able to develop better treatments to help with problems like depression and substance use. This study is intended for individuals that are HIV p…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* 18-59 years old
* Weekly use of stimulants reported in the past month or a score of 4 or more on the Alcohol, Smoking and Substance Involvement Screening Test (ASSIST)
* Confirmed HIV diagnosis
* Current receipt of daily oral antiretroviral therapy (ART) medication
* English f…
Contacts