Sleep TMS for Major Depression

Sleep TMS for Depression

Recruiting N/A Interventional Study
Major Depression Sleep
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Healthy Volunteers Welcome You do not need to have the condition being studied to take part.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 – 65
Sex
Any
Study type
Interventional
Purpose
Basic Science
Participants needed
55 (estimated)
Sponsor
Stanford University · Other
Who this trial is looking for

This trial is looking for adults with major depression who have not responded to previous antidepressants. Participants will receive a new treatment called sleep-state transcranial magnetic stimulation to see if it helps improve their condition.

Are You a Good Fit for This Trial?
Must not be taking AntidepressantsAntipsychotics
Rules you out Major psychiatric conditionsNeurological conditionsSubstance use disordersMedical conditions affecting brain function

You may be able to join if

  • I am between 18 and 65 years old
  • I have been diagnosed with major depressive disorder
  • I have not responded to at least one antidepressant medication
  • I have moderate to severe depression
  • I have been on a steady dose of antidepressant medication for at least 6 weeks
  • I am a healthy adult without current major depressive symptoms

You may not be able to join if

  • I have an intellectual disability
  • I have had a significant head injury or a neurological disorder
  • I am pregnant or have given birth recently
  • I have any conditions that prevent me from undergoing TMS or MRI
  • I currently use substances or have thoughts of suicide

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.

Check Your Eligibility
About This Trial

The goal of this study is to establish the feasibility, tolerability, and preliminary efficacy of sleep-state transcranial magnetic stimulation (TMS) for enhancing plasticity in depression treatment.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Adults ages 18-65 years * Current Major Depressive Disorder (MDD) diagnosis * Failed ≥1 antidepressant medication * Moderate-to-severe depression * Stable antidepressant medication dose for ≥ 6 weeks prior to enrollment * Healthy control participants are adults ages 18-65 year…
Contacts

Hansong Lee, MS

408-909-2203

kellerlab@stanford.edu

CONTACT