rTMS Treatment for Knee Arthritis Pain and Depression
A Randomized Pilot rTMS Trial for Knee Arthritis Pain and Depression
Recruiting
Early Phase 1
Interventional Study
Knee Osteoarthritis
Depression
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 50 – 95
- Sex
- Any
- Trial phase
- Early Phase 1
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 30 (estimated)
- Sponsor
- University of California, Los Angeles · Other
Who this trial is looking for
This trial is looking for people aged 50 or older who have chronic knee pain and depression. Participants will attend Tai Chi sessions and receive rTMS treatment twice a week for three months.
Are You a Good Fit for This Trial?
You may be able to join if
- I am 50 years old or older.
- I have chronic pain in my body for 6 months or more.
- I have knee pain for at least 3 months on most days.
- I have a pain interference score of 40 or higher.
- I have internet access.
- I can walk without assistance.
- I have depression with a score over 20 on the Beck Depression Inventory.
- I am willing to complete the 3-month study with follow-ups.
You may not be able to join if
- I have changed my psychotropic or pain medication in the past four months.
- I am currently diagnosed with mania, hypomania, or a psychotic disorder.
- I have a serious medical condition like cancer or heart disease.
- I cannot safely participate in moderate exercise.
- I have had alcohol or drug dependence in the past three months.
- I am currently practicing Tai Chi.
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
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About This Trial
Osteoarthritis (OA) is a major public health problem, and involvement of the knee is especially disabling. Symptomatic knee OA has an incidence rate between 40 to 1,020 per 100,000 person years1 and is among the most common causes of disability worldwide. Knee arthritis pain and disability are highly comorbid wiht depression (30-50%). Currently available treatments offer only limited relief. The P…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* • Age 50 or years older.
* Chronic pain as indicated by complaints of pain in one or more body regions for 6 months or more. Participants who meet at least one of the following criteria for Osteoarthritis (OA)
* Fulfills the American College of Rheumatology (ACR) crite…
Contacts
No contact information available.