No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
50 – 90
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
99 (estimated)
Sponsor
University of Nebraska · Other
Who this trial is looking for
This trial is looking for older adults who have had COVID-19 and continue to experience symptoms like fatigue. Participants will receive home treatment using lower-body heat therapy to improve their physical function and health.
Are You a Good Fit for This Trial?
You may be able to join if
I am between 50 and 90 years old.
I can do leg exercises without orthopedic limitations.
I have a BMI under 40 and weigh less than 400 pounds.
I had COVID-19 and have had ongoing symptoms for at least 2 months.
You may not be able to join if
I cannot give written consent.
I am pregnant, breastfeeding, or plan to become pregnant in the next 6 months.
I am on hormone therapy.
I have claustrophobia.
I have orthopedic limitations that prevent me from walking.
I am currently in an exercise or respiratory muscle rehab program.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
Post-acute sequelae of SARS-CoV-2 infection (PASC) is becoming a major risk factor for chronic diseases, with older adults and those with underlying health conditions at risk of developing persistent mobility limitations and disabilities. Although exercise intervention is a common strategy to restore functional capacity, it may not be feasible or enticing to many people with PASC. This clinical tr…
Post-acute sequelae of SARS-CoV-2 infection (PASC) is becoming a major risk factor for chronic diseases, with older adults and those with underlying health conditions at risk of developing persistent mobility limitations and disabilities. Although exercise intervention is a common strategy to restore functional capacity, it may not be feasible or enticing to many people with PASC. This clinical trial seeks to establish the tolerability and efficacy of at home lower-body heat therapy for improving functional capacity along with metabolic and vascular health in late-middle aged and older adults with PASC, also known as "long COVID".
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Between the ages of 50 and 90 years
* Free from orthopedic limitations that would prohibit performing leg exercise
* BMI \< 40 kg/m2 and weigh \< 400lbs
* Previously contracted Covid-19 and have persistent symptoms such as a fatigue or decline in physical function, for at leas…
Inclusion Criteria:
* Between the ages of 50 and 90 years
* Free from orthopedic limitations that would prohibit performing leg exercise
* BMI \< 40 kg/m2 and weigh \< 400lbs
* Previously contracted Covid-19 and have persistent symptoms such as a fatigue or decline in physical function, for at least 2 months following SARS-CoV-2 infection
Exclusion Criteria:
* Unable to give written informed consent
* Women who are pregnant, breastfeeding, or likely to become pregnant within the next 6 months
* Claustrophobia
* Orthopedic limitations that would prohibit them from walking
* Currently enrolled in an exercise-based or respiratory muscle rehabilitation program.
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