TMS and Language Therapy for Aphasia After Stroke
Transcranial Magnetic Stimulation + Language Therapy to Treat Subacute Aphasia
Recruiting
Phase 2
Interventional Study
Stroke
Aphasia
Aphasia Following Cerebral Infarction
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 18 – 85
- Sex
- Any
- Trial phase
- Phase 2
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 63 (estimated)
- Sponsor
- University of Pennsylvania · Other
Who this trial is looking for
This trial is looking for people who had a stroke 2 to 6 weeks ago and are experiencing difficulties with speaking. Participants will receive treatment that combines Transcranial Magnetic Stimulation and language therapy over 10 sessions, with follow-ups after treatment.
Are You a Good Fit for This Trial?
You may be able to join if
- I have had a stroke in the left side of my brain.
- My stroke occurred 2 to 6 weeks before joining this trial.
- I can understand the study and give my consent.
- I can speak and understand English.
- I am right-handed.
You may not be able to join if
- I have serious ongoing issues with substance abuse.
- I have had a head injury that caused me to lose consciousness for more than 5 minutes.
- I have a history of major psychiatric illness.
- I have dementia or other neurological conditions.
- I have epilepsy or had a seizure after my stroke.
- I have a pacemaker.
- I have been diagnosed with tinnitus.
- I am pregnant.
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
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About This Trial
The goal of this clinical trial is to determine if Transcranial Magnetic Stimulation (TMS) combined with modified Constraint Induced Language Therapy (mCILT) is an effective treatment for aphasia when delivered in the subacute stage after stroke.
The main questions this study aims to answer are:
1. Can TMS combined with mCILT improve overall speech?
2. Can we identify specific behavioral and bio…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Left hemisphere stroke resulting in aphasia
* The stroke must have occurred between 2 and 6 weeks prior to enrollment
* Must be able to understand the nature of the study, and give informed consent
* English proficiency
* Right-handed
Exclusion Criteria:
* History of serious…
Contacts