Transcranial Magnetic Stimulation + Language Therapy to Treat Subacute Aphasia

Recruiting Phase 2 Interventional Study
Stroke Aphasia Aphasia Following Cerebral Infarction
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
18 – 85
Sex
Any
Trial phase
Phase 2
Study type
Interventional
Purpose
Treatment
Participants needed
63 (estimated)
Sponsor
University of Pennsylvania · Other
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About This Trial
The goal of this clinical trial is to determine if Transcranial Magnetic Stimulation (TMS) combined with modified Constraint Induced Language Therapy (mCILT) is an effective treatment for aphasia when delivered in the subacute stage after stroke. The main questions this study aims to answer are: 1. Can TMS combined with mCILT improve overall speech? 2. Can we identify specific behavioral and bio…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Left hemisphere stroke resulting in aphasia * The stroke must have occurred between 2 and 6 weeks prior to enrollment * Must be able to understand the nature of the study, and give informed consent * English proficiency * Right-handed Exclusion Criteria: * History of serious…
Contacts

Leslie Vnenchak, MA, CCC-SLP

215-964-2502

leslie.vnenchak@pennmedicine.upenn.edu

CONTACT

Daniela Sacchetti, MS

215-964-2502

danielas@pennmedicine.upenn.edu

CONTACT