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BMS-986500 for Advanced Solid Tumors

A Phase 1 Study of BMS-986500 as Monotherapy or Combination Therapy in Advanced Solid Tumors

Recruiting Phase 1 Interventional Study
Advanced Solid Tumor Advanced Breast Cancer Advanced Ovarian Cancer
More trials: Breast Cancer clinical trials· Breast Cancer trials in Alabama
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 and older
Sex
Any
Trial phase
Phase 1
Study type
Interventional
Purpose
Treatment
Participants needed
234 (estimated)
Sponsor
Bristol-Myers Squibb · Industry
Who this trial is looking for

This trial is looking for adults with advanced solid tumors to test the drug BMS-986500. Participants may receive this drug alone or with other treatments, depending on their specific cancer type.

Are You a Good Fit for This Trial?

You may be able to join if

  • I am at least 18 years old.
  • I have a confirmed diagnosis of a solid tumor that cannot be surgically removed.
  • I have measurable disease as defined by medical standards.
  • I have a stable performance status indicating I am well enough to participate.
  • I have CCNE1-amplified ovarian cancer (for Part 2A only).

You may not be able to join if

  • I have active brain metastasis.
  • I have serious heart problems.
  • I have a bleeding disorder or significant bleeding in the last 3 months.
  • I have moderate or severe nerve damage.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.

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About This Trial

The purpose of this study is to assess BMS-986500 as monotherapy in advanced solid tumors and as combination therapy in CDK4/6 inhibitor pre-treated advanced breast cancer.

Trial Locations

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Eligibility Criteria
Inclusion Criteria: * Participants must be ≥ 18 years of age. * Participants must have histologically confirmed diagnosis of a locally advanced, unresectable, or metastatic solid tumor malignancy. * Participants must have a measurable disease per Response Evaluation Criteria in Solid Tumors (RECIST…
Contacts

BMS Clinical Trials Contact Center www.BMSClinicalTrials.com, www.BMSStudyConnect.com

855-907-3286

Clinical.Trials@bms.com

CONTACT

First line of the email MUST contain NCT # and Site #.

CONTACT

NCT ID: NCT06997029 Source: ClinicalTrials.gov