Brain Stimulation for Depression and Suicidal Thoughts

Accelerated Intermittent Theta Burst Stimulation for Adolescent and Young Adult Depression With Elevated Suicide Risk

Recruiting N/A Interventional Study
Major Depressive Disorder (MDD) Suicidal Ideation
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
15 – 25
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
25 (estimated)
Sponsor
University of California, Davis · Other
Who this trial is looking for

This trial is looking for young people aged 15 to 25 who have depression and suicidal thoughts. Participants will receive a quick brain stimulation treatment over 5 days and undergo brain scans to see if it helps them feel better.

Are You a Good Fit for This Trial?
Must not be taking Benzodiazepines
Rules you out Active substance useUntreated psychosis

You may be able to join if

  • I speak English
  • I can give informed consent
  • I am 15 to 25 years old
  • I was recently discharged from the emergency department for suicidal thoughts
  • I have been diagnosed with major depressive disorder

You may not be able to join if

  • I cannot provide consent due to a medical condition or mental illness
  • I am taking medications that interfere with TMS treatment
  • I currently use drugs or alcohol actively
  • I have untreated, active psychosis
  • I am breastfeeding, pregnant, or planning a pregnancy
  • I have participated in another clinical study in the past 30 days
  • I have conditions that prevent me from receiving TMS or MRI

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

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About This Trial
The goal of this clinical trial is to learn if a fast-acting brain stimulation treatment called transcranial magnetic stimulation (TMS) can help people with depression and suicidal thoughts. The treatment is non-invasive (does not involve surgery or medications), is given over 5 days, and uses brain imaging (MRI) to guide which part of the brain to target. This study tests whether this treatment i…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * English speaking * Able to provide informed consent * age 15-25 years * Discharged within the past week from the ED for chief complaint of SI OR recently admitted in urgent health care setting or seen in outpatient clinic for depression-related suicidal ideation * Meets MDD cr…
Contacts

Se Ri (Sally) Bae, MD

213-340-4006

sebae@ucdavis.edu

CONTACT