No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
15 – 25
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
25 (estimated)
Sponsor
University of California, Davis · Other
Who this trial is looking for
This trial is looking for young people aged 15 to 25 who have depression and suicidal thoughts. Participants will receive a quick brain stimulation treatment over 5 days and undergo brain scans to see if it helps them feel better.
Are You a Good Fit for This Trial?
Must not be takingBenzodiazepines
Rules you outActive substance useUntreated psychosis
You may be able to join if
I speak English
I can give informed consent
I am 15 to 25 years old
I was recently discharged from the emergency department for suicidal thoughts
I have been diagnosed with major depressive disorder
You may not be able to join if
I cannot provide consent due to a medical condition or mental illness
I am taking medications that interfere with TMS treatment
I currently use drugs or alcohol actively
I have untreated, active psychosis
I am breastfeeding, pregnant, or planning a pregnancy
I have participated in another clinical study in the past 30 days
I have conditions that prevent me from receiving TMS or MRI
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
The goal of this clinical trial is to learn if a fast-acting brain stimulation treatment called transcranial magnetic stimulation (TMS) can help people with depression and suicidal thoughts. The treatment is non-invasive (does not involve surgery or medications), is given over 5 days, and uses brain imaging (MRI) to guide which part of the brain to target. This study tests whether this treatment i…
The goal of this clinical trial is to learn if a fast-acting brain stimulation treatment called transcranial magnetic stimulation (TMS) can help people with depression and suicidal thoughts. The treatment is non-invasive (does not involve surgery or medications), is given over 5 days, and uses brain imaging (MRI) to guide which part of the brain to target. This study tests whether this treatment is a helpful and practical option for adolescents and young adults who are depressed and have suicidal thoughts.
We want to see if:
1. This treatment is feasible and acceptable to patients
2. It can reduce depression and suicidal thoughts
3. It can lower the chance of going to the hospital
4. It affects daily functioning (school, work, relationships)
All participants will undergo 5-days of TMS treatment and complete MRI brain scans before and after treatment. They will return for check-ups after 1 week and 4 weeks.
Trial Locations
Loading…
Loading trial locations…
Facility
City
State
Country
Status
Eligibility Criteria
Inclusion Criteria:
* English speaking
* Able to provide informed consent
* age 15-25 years
* Discharged within the past week from the ED for chief complaint of SI OR recently admitted in urgent health care setting or seen in outpatient clinic for depression-related suicidal ideation
* Meets MDD cr…
Inclusion Criteria:
* English speaking
* Able to provide informed consent
* age 15-25 years
* Discharged within the past week from the ED for chief complaint of SI OR recently admitted in urgent health care setting or seen in outpatient clinic for depression-related suicidal ideation
* Meets MDD criteria per the Mini International Neuropsychiatric Interview (MINI)
Exclusion Criteria:
* Unable to consent (due to medical condition, psychosis, substance use, etc)
* Use of benzodiazepines or medications that would interfere with TMS treatment as per PI discretion
* Active substance use or severe substance use that in the opinion of the PI would interfere with study participation
* Untreated, active psychosis
* Female patient who is breastfeeding, pregnant or who is planning a pregnancy during the study
* Participation in any clinical study with exposure to any investigational treatment or product within the previous 30 days, or plan on concurrent participation in other studies
* Contraindications to receiving TMS and/or MRI as determined by screening questionnaires
Picking one helps us show the most relevant trials first.
Your results are loading in the background — you can
change this any time from the results page.
Set your location to continue
Find My Trials uses your location to surface clinical trials near you.
Add your city or zip code to your profile and try again.