Exosome Response to Meals in Obesity
Upper Body Subcutaneous Exosome Release in Response to a Meal in Obesity
Recruiting
N/A
Interventional Study
Obesity
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 18 – 55
- Sex
- Any
- Study type
- Interventional
- Purpose
- Basic Science
- Participants needed
- 20 (estimated)
- Sponsor
- Mayo Clinic · Other
Who this trial is looking for
This trial is looking for premenopausal women who are interested in how fat tissue responds to meals. Participants will undergo a procedure to help researchers study the fat tissue's reaction after eating a meal.
Are You a Good Fit for This Trial?
You may be able to join if
- I am a woman
- I am premenopausal
You may not be able to join if
- I take medications that affect blood flow
- I have diabetes
- I have a history of cardiovascular disease
- I am allergic to lidocaine
- I am post-menopausal
- I am pregnant
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
Check Your Eligibility
About This Trial
The purpose of this study is to understand the specific outflow and difference between normal weight and volunteers with obesity of upper body subcutaneous adipose tissue in response to a mixed meal challenge by site specific cannulation of the superior epigastric vein. We will characterize the exosome signatures in response to a meal and compare to the exosome signature of arterialized venous pla…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
• All women must be premenopausal
Exclusion Criteria:
* Participants taking medications know to affect blood flow (statins, β-blockers) or fatty acid or adipose tissue metabolism (TZDs, high dose fish oil supplements)
* Diabetes, history of cardiovascular disease
* Allergy to …
Contacts