No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
6 – 12
Sex
Any
Study type
Interventional
Purpose
Supportive Care
Participants needed
60 (estimated)
Sponsor
University of Washington · Other
Who this trial is looking for
This trial is looking for children aged 6-12 years old with asthma. Participants will work with a community health worker to test the effects of HEPA air cleaners on indoor air quality and asthma health over three months.
Are You a Good Fit for This Trial?
You may be able to join if
I am 6-12 years old.
I have been diagnosed with asthma by a healthcare provider.
My caregiver is comfortable participating in English.
My caregiver knows about my daily asthma health.
I live within 10 miles of Seattle-Tacoma International Airport.
I live with my caregiver at least five nights a week.
I have no plans to move in the next three months.
You may not be able to join if
I have severe asthma.
I have reported asthma symptoms every day for the past 14 days.
I have been hospitalized for asthma two or more times in the past 12 months.
There are multiple people with asthma in my household eligible for the program.
There are multiple people with severe asthma in my household.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
For children with asthma, exposure to indoor air pollution increases the risk of a serious asthma exacerbation, which can be life-threatening. Interventions aimed at improving indoor air quality, including use of a portable air cleaner with a high-efficiency particulate air (HEPA) filter, can reduce this risk, but the effectiveness, feasibility and acceptability of HEPA air cleaners varies by sett…
For children with asthma, exposure to indoor air pollution increases the risk of a serious asthma exacerbation, which can be life-threatening. Interventions aimed at improving indoor air quality, including use of a portable air cleaner with a high-efficiency particulate air (HEPA) filter, can reduce this risk, but the effectiveness, feasibility and acceptability of HEPA air cleaners varies by setting. In collaboration with a community health worker (CHW) delivered asthma education program, the investigators are conducting a randomized clinical trial to evaluate the effectiveness of HEPA air cleaners to improve indoor air quality and child asthma health in South King County of Washington state, a vulnerable community impacted by air pollution from airports and highway traffic. Key features of the Airports, Air Quality and Asthma (AAA) design include integration of CHWs into study procedures, including CHWs recruited from community-based organizations, into multiple aspects of the trial protocol. The investigators aim to recruit up to N=60 children with asthma randomized into intervention and control groups in a 1:1 ratio, conduct baseline assessments of indoor air quality and airway health, and collect repeated assessments of air quality and airway health during the three-month intervention period and after the trial concludes. Study findings will inform future approaches to integrate HEPA air cleaners into existing CHW asthma education programs in this and similar communities.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Child is 6-12 years old with a health care provider-diagnosed asthma.
* Caregiver is comfortable in participating in all study activities in English (communicating with study staff by phone and completing online surveys).
* Caregiver is familiar with the child's daily asthma h…
Inclusion Criteria:
* Child is 6-12 years old with a health care provider-diagnosed asthma.
* Caregiver is comfortable in participating in all study activities in English (communicating with study staff by phone and completing online surveys).
* Caregiver is familiar with the child's daily asthma health.
* Residence within 10 miles of Seattle-Tacoma International Airport as determined by zip code
* Child resides in caregiver's home at least five nights a week on a regular basis and has no plans to move in the next three months.
Exclusion Criteria:
* Child has severe asthma at baseline. Severe asthma was defined in consultation with pediatric pulmonologists to be caregiver-reported asthma symptoms every day over the past 14 days and/or two or more inpatient hospitalizations for asthma in the past 12 months.
* Households were excluded if there were multiple individuals within the same household with asthma eligible for the King County CHW Asthma Program or had severe asthma.
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