Combining rTMS & Aerobic Exercise to Treat Depression and Improve Post-Stroke Walking
Recruiting
N/A
Interventional Study
Stroke
Depression - Major Depressive Disorder
Walking Impairment
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About This Trial
Investigators primary aim is to carry out a two-site, randomized, double-blind, sham-controlled, phase II trial to systematically examine the potential for aerobic exercise (AEx) to enhance the anti-depressant benefits of rTMS in individuals with post-stroke depression (PSD).
Investigators propose to determine the efficacy of combining two known anti-depressant treatments shown to be effective in…
Trial Locations
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Eligibility Criteria
Inclusion criteria:
* age \>21
* stroke at least 12 months prior
* screen positive for depressive symptoms (PHQ-9 \> 5) and HAM-D17 ≥ 12
* residual paresis in the lower extremity (Fugl-Meyer LE motor score \<34)
* ability to walk without assistance and without an AFO at speeds ranging from 0.2-1.0 …
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