Gamma-glutamylcysteine for Parkinson's Disease Patients

Enrichment of Glutathione Using Gamma-glutamylcysteine Supplementation in Parkinson's Disease Patients.

Recruiting Phase 1 Interventional Study
Parkinsons Disease (PD)
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
50 – 80
Sex
Any
Trial phase
Phase 1
Study type
Interventional
Purpose
Prevention
Participants needed
12 (estimated)
Sponsor
Pravat Mandal · Other
Who this trial is looking for

This trial is looking for people with early Parkinson's disease to see how a supplement called gamma-glutamylcysteine affects their health. Participants will take the supplement and have their brain, blood, and gut health checked over time.

Are You a Good Fit for This Trial?

You may be able to join if

  • I have been diagnosed with Parkinson's disease.
  • I have a MoCA score of 26 or higher.
  • I am between 50 and 80 years old.
  • I can read and write in English.

You may not be able to join if

  • I have a pacemaker or other implants in my body.
  • I have a history of cancer.
  • I have had a head injury in the past.
  • I have active psychosis or delirium.
  • I have chronic kidney or liver disease.
  • I have Parkinson's disease dementia.
  • I am taking antioxidant therapies.
  • I have claustrophobia.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.

Check Your Eligibility
About This Trial
This study is designed l to evaluate the effects of GGC oral supplementation in early Parkinson's disease (PD) patients. The main objectives of the study are to evaluate: 1. To study the enrichment of master antioxidant, glutathione (GSH) levels in brain and blood of these PD patients compared to baseline due to GGC supplementation. 2. To study the changes in motor function, cognitive skills in P…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Confirmed Parkinson's Disease diagnosis. * Montreal Cognitive Assessment (MoCA) greater than or equal to 26. * Age (50 to 80 years of age). * Ability to read and write in English. Exclusion Criteria: * Presence of pacemakers, aneurysm clips, artificial heart valves, ear impl…
Contacts

Pravat K MANDAL, PHD

4126999561

mandalpk@pitt.edu

CONTACT

Nazia Pillar, M.S

878-670-3123

naa430@pitt.edu

CONTACT