Glucose Study for Multiple Sclerosis
Glucose Consumption in MS Using [F-18]FDG-PET
Recruiting
Phase 4
Interventional Study
Multiple Sclerosis
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 18 – 70
- Sex
- Any
- Trial phase
- Phase 4
- Study type
- Interventional
- Purpose
- Diagnostic
- Participants needed
- 50 (estimated)
- Sponsor
- Brigham and Women's Hospital · Other
Who this trial is looking for
This trial is looking for people with multiple sclerosis and healthy individuals to help understand how glucose is used in the brain. Participants will undergo imaging tests with PET and MRI to compare brain activity and health.
Are You a Good Fit for This Trial?
You may be able to join if
- I am between 18 and 70 years old.
- I have been diagnosed with multiple sclerosis.
- I am willing to undergo PET and MRI imaging.
- I can give informed consent.
You may not be able to join if
- I have a known alternate neurological disorder.
- I have a known alternate neuropsychiatric disorder.
- I have other medical conditions that prevent me from participating.
- I am pregnant or nursing.
- I have claustrophobia.
- I have a non-MRI compatible implanted device.
- I have taken corticosteroids in the past four weeks.
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
Check Your Eligibility
About This Trial
Given the need for better diagnostic imaging techniques in multiple sclerosis (MS), the study aims to investigate the utility of \[F-18\]FDG positron emission tomography (PET) in MS. The study will be assessing glucose consumption patterns in subjects with progressive MS (PMS) and relapsing-remitting MS (RRMS), as well as healthy controls. PET will be compared to magnetic resonance imaging (MRI) l…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
1. Age 18 to 70 years.
2. Subjects meeting the definition for MS (including SPMS, RRMS or PPMS) by International Panel (2017 McDonald) Criteria. Age and sex-matched healthy controls will also be recruited.
3. Subjects willing to undergo PET and MRI imaging.
4. Subjects willing a…
Contacts