No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
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You do not need to have the condition being studied to take part.
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Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 – 55
Sex
Any
Study type
Interventional
Purpose
Other
Participants needed
20 (estimated)
Sponsor
Ball State University · Other
Who this trial is looking for
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
Based on prior research, the investigators are interested in whether an intervention targeting gut health (supplemental fiber for 9 weeks total) will improve vascular health in individuals with obesity. Additionally, the investigators are interested in if this response differs based on whether individuals with obesity have very few heart disease risk factors or several heart disease risk factors.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Participants are 18-55 years old.
* Participants BMI is ≥30 kg/m2 - this BMI requirement is due to our research aims.
* Participants have either 0-1 or 2+ of the following risk factors outside of the normal reference ranges: blood pressure, blood sugar, triglycerides, and HDL-…
Inclusion Criteria:
* Participants are 18-55 years old.
* Participants BMI is ≥30 kg/m2 - this BMI requirement is due to our research aims.
* Participants have either 0-1 or 2+ of the following risk factors outside of the normal reference ranges: blood pressure, blood sugar, triglycerides, and HDL-cholesterol.
* Participants are not pregnant or expecting to become pregnant (females only). •Participants are not postmenopausal (females only).
* Participants have not been diagnosed with an advanced cardiometabolic condition (e.g., cardiovascular disease, type 2 diabetes).
* Participants have not been diagnosed with a chronic inflammatory condition (e.g., rheumatoid arthritis, inflammatory bowel disease, diverticulosis/diverticulitis).
* Participants do not regularly take anti-inflammatory drugs (more than 2x week) and are willing to suspend use of these medications for 3 days leading up to in-lab visits.
* Participants do not take weight-loss medications (e.g., Ozempic, Wegovy).
* Participants do not use tobacco products or any illicit drugs.
* Participants have not used antibiotics or probiotics in the last month.
* Participants do not have dietary restrictions prohibiting them from consuming the fiber supplement (e.g., food allergies/intolerance).
* Participants do not have a pacemaker.
* Participants are able to lie on their back (supine position) in the dark for at least 10 minutes (related to vascular measurements).
Exclusion Criteria:
* Participants are not 18-55 years old.
* Participants BMI is not ≥30 kg/m2 - this BMI requirement is due to our research aims.
* Participants do not have either 0-1 or 2+ of the following risk factors outside of the normal reference ranges: blood pressure, blood sugar, triglycerides, and HDL-cholesterol.
* Participants are pregnant or expecting to become pregnant (females only).
* Participants are postmenopausal (females only).
* Participants have been diagnosed with an advanced cardiometabolic condition (e.g., cardiovascular disease, type 2 diabetes).
* Participants have been diagnosed with a chronic inflammatory condition (e.g., rheumatoid arthritis, inflammatory bowel disease, diverticulosis/diverticulitis). •Participants regularly take anti-inflammatory drugs (more than 2x week) and are not willing to suspend use of these medications for 3 days leading up to in-lab visits.
* Participants take weight-loss medications (e.g., Ozempic, Wegovy).
* Participants use tobacco products or any illicit drugs.
* Participants have used antibiotics or probiotics in the last month.
* Participants have dietary restrictions prohibiting them from consuming the fiber supplement (e.g., food allergies/intolerance).
* Participants have a pacemaker.
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