MBX 4291 for Obesity

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of MBX 4291 in Adult Participants With Obesity

Recruiting Phase 1 Interventional Study
Obesity
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 – 65
Sex
Any
Trial phase
Phase 1
Study type
Interventional
Purpose
Treatment
Participants needed
124 (estimated)
Sponsor
MBX Biosciences · Industry
Who this trial is looking for

This trial is looking for adults with obesity to test a new treatment called MBX 4291. Participants will receive the treatment through injections to help us understand how safe it is and how it works in the body.

Are You a Good Fit for This Trial?

You may be able to join if

  • I am between 19 and 65 years old.
  • I have a BMI between 30 and 50.
  • I have not had a significant change in weight of more than 5% in the last 3 months.

You may not be able to join if

  • I have a serious illness that might prevent me from joining the study.
  • I currently have pancreatitis.
  • I have type 1 or type 2 diabetes.
  • I have underlying causes of obesity like endocrine disorders.
  • I have a personal or family history of medullary thyroid carcinoma.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.

Check Your Eligibility
About This Trial

The purpose of this study is to evaluate the safety and tolerability of single and multiple subcutaneous (SC) doses of MBX 4291 in adults with obesity.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Age of \>18 to ≤65 years at the time of signing the informed consent. * Has a BMI of ≥30 to \<50 kg/m2 at screening and baseline. * Weight-stable, i.e., no more than ±5% change in body weight for at least 3 months prior to screening and between screening and baseline. Exclusi…
Contacts

Elisa Fabbrini, MD, PhD

844-877-4473

MBX4291.Clinicaltrials@mbxbio.com

CONTACT

Stewart Hallett

844-877-4473

MBX4291.Clinicaltrials@mbxbio.com

CONTACT