Airsupra for Acute Asthma Treatment

45th Multicenter Airway Research Collaboration

Recruiting Phase 4 Interventional Study
Asthma Acute Asthma Exacerbation Asthma Asthma Control Level
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 – 54
Sex
Any
Trial phase
Phase 4
Study type
Interventional
Purpose
Treatment
Participants needed
1,860 (estimated)
Sponsor
Massachusetts General Hospital · Other
Who this trial is looking for

This trial is looking for adults with acute asthma to see if starting Airsupra in the emergency department helps prevent future asthma episodes. Participants will use Airsupra as their rescue inhaler for 3 months.

Are You a Good Fit for This Trial?
Must not be taking Systemic corticosteroids
Rules you out COPDChronic bronchitisEmphysemaPneumoniaSignificant cardiovascular diseaseSignificant cancer

You may be able to join if

  • I have acute asthma
  • I am between 18 to 54 years old
  • I speak English or Spanish
  • I will be discharged from the emergency department with a short course of corticosteroids
  • I am willing to use Airsupra as my rescue inhaler for the next 3 months
  • I can demonstrate how to properly use an inhaler
  • I will provide informed consent to join the study

You may not be able to join if

  • I have been involved in planning or conducting this study
  • I have participated in this study before
  • I have been diagnosed with COPD, chronic bronchitis, or emphysema
  • I have used systemic corticosteroids in the past 2 weeks
  • I am in another clinical study with an investigational product
  • I currently have pneumonia
  • I have significant heart disease or cancer
  • I am currently pregnant or breastfeeding

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

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About This Trial

The study is a randomized controlled trial on the effect of emergency department initiation of Airsupra on acute asthma "recurrence" at 3 months and other related outcomes (acute asthma relapse, asthma control).

Trial Locations
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Eligibility Criteria
INCLUSION CRITERIA: * acute asthma * age 18.0 to 54.9 years * English and/or Spanish speaking * decision by ED attending to discharge patient to home on short course of systemic corticosteroids * (intervention group only) Willingness to use Airsupra as their rescue inhaler for next 3 months * demon…
Contacts

Carlos A Camargo, MD, DrPH

617-726-5276

ccamargo@mgb.org

CONTACT