No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 – 85
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
12 (estimated)
Sponsor
Rutgers, The State University of New Jersey · Other
Who this trial is looking for
This trial is looking for people who have had a stroke and now have reading difficulties. Participants will receive two types of reading treatment over a few weeks to see which one works better.
Are You a Good Fit for This Trial?
You may be able to join if
I speak English fluently as my first language before my stroke.
I have normal or corrected-to-normal vision.
I have normal or aided hearing.
I had a left hemisphere stroke confirmed by a brain scan.
I have significant reading difficulties as shown by a reading test.
You may not be able to join if
I have a neurological disease affecting my brain diagnosed before my stroke.
I have severe speech problems as judged by speech specialists.
I have a history of learning disabilities like developmental dyslexia.
I have major psychiatric disorders that I currently report.
I cannot provide a post-stroke brain scan.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
This study is a low-risk, early phase 1, multicenter trial to test the use of a computational (neural network) cognitive model of reading to simulate acquired dyslexia and its treatment. The aim is to determine whether there is an advantage to receiving the treatment the model predicts to be advantageous compared to the alternative treatment. All participants will receive two full rounds of treatm…
This study is a low-risk, early phase 1, multicenter trial to test the use of a computational (neural network) cognitive model of reading to simulate acquired dyslexia and its treatment. The aim is to determine whether there is an advantage to receiving the treatment the model predicts to be advantageous compared to the alternative treatment. All participants will receive two full rounds of treatment. A round of treatment will consist of either phonomotor treatment (PMT) or semantic feature analysis (SFA) for 60 hours, distributed over 5 days a week for 2 hours a day.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Fluent in English as a first language pre-stroke by self report.
* Normal or corrected-to-normal vision.
* Normal or aided hearing.
* Left hemisphere ischemic or hemorrhagic stroke (as verified by a structural brain scan).
* Impaired reading as confirmed by significant impairm…
Inclusion Criteria:
* Fluent in English as a first language pre-stroke by self report.
* Normal or corrected-to-normal vision.
* Normal or aided hearing.
* Left hemisphere ischemic or hemorrhagic stroke (as verified by a structural brain scan).
* Impaired reading as confirmed by significant impairment in the Basic Skills cluster of the Woodcock Reading Mastery Test - III.
Exclusion Criteria:
* Diagnosed pre-stroke neurological disease affecting the brain other than left hemisphere stroke.
* Severe apraxia of speech (determined by consensus judgment among speech-language pathologists).
* History of learning disabilities such as developmental dyslexia or current self-reported major psychiatric disorders.
* Inability to undergo, or provide a copy of, a post-stroke brain imaging scan.
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