No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 and older
Sex
Any
Trial phase
Phase 2
Study type
Interventional
Purpose
Treatment
Participants needed
80 (estimated)
Sponsor
University of California, Los Angeles · Other
Who this trial is looking for
This trial is looking for adults with low positive feelings and depression. Participants will take part in either a Virtual Reality-Reward Training or a Virtual Reality-Memory Training program over 7 weeks, including VR sessions and some assessments.
Are You a Good Fit for This Trial?
You may be able to join if
I am at least 18 years old
I understand written and spoken English
I have a depression score of 8 or higher
I have a positive affect score of 27 or lower
I have a functioning score of 11 or higher
You may not be able to join if
I have a history of bipolar disorder or psychosis
I have had a substance use disorder in the past 6 months
I currently take psychotropic medications
I am currently pregnant or planning to become pregnant
I often experience motion sickness
I have had seizures in the last year or have epilepsy
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
The purpose of this study is to compare the effects of Virtual Reality-Reward Training (VR-RT) with an active control condition, Virtual Reality-Memory Training (VR-MT), on positive affect and other clinical symptoms.
VR-RT is a novel intervention aimed at enhancing savoring of positive experiences among individuals with elevated depression and low positive affect through guided imaginal recounti…
The purpose of this study is to compare the effects of Virtual Reality-Reward Training (VR-RT) with an active control condition, Virtual Reality-Memory Training (VR-MT), on positive affect and other clinical symptoms.
VR-RT is a novel intervention aimed at enhancing savoring of positive experiences among individuals with elevated depression and low positive affect through guided imaginal recounting following immersion in positive VR experiences. The current study tests an enhanced version of this training using improved virtual reality technology.
Target enrollment is 80 participants with low positive affect, depression, and impaired functioning, who are at least 18 years old, who will be randomly assigned to 4 weeks of either VR-RT or VR-MT. Participants will complete in-person VR sessions, laboratory assessments, and self-report questionnaires as part of the study.
The total length of participation is around 3 months.
Trial Locations
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City
State
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Status
Eligibility Criteria
Inclusion Criteria:
1. At least 18 years old
2. Fluent in written and spoken English
3. Meet all of the following dimensional score cutoffs:
1. Score on the DASS-21 depression subscale must be ≥ 8
2. Score on the PANAS-P of 27 or lower
3. Score on the WSAS of ≥ 11
Exclusion Criteria:
1.…
Inclusion Criteria:
1. At least 18 years old
2. Fluent in written and spoken English
3. Meet all of the following dimensional score cutoffs:
1. Score on the DASS-21 depression subscale must be ≥ 8
2. Score on the PANAS-P of 27 or lower
3. Score on the WSAS of ≥ 11
Exclusion Criteria:
1. Lifetime history of schizophrenia, bipolar disorder, psychosis, intellectual/developmental disability, or organic brain damage
2. Substance use disorder in the past 6 months
3. Current use of psychotropic medications
4. Currently pregnant or planning to become pregnant
5. Self-reported frequent motion sickness
6. Self-reported seizures within the last year and/or a diagnosis of epilepsy
7. Self-reported color blindness or vision that is not corrected to normal
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