No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
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Review the details below, then apply to join this clinical trial.
At a Glance
Age
14 – 17
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
108 (estimated)
Sponsor
Yale University · Other
Who this trial is looking for
This trial is looking for adolescents with anxiety disorders and their parents to test a specific parenting treatment. Participants will undergo assessments and receive treatment aimed at improving anxiety symptoms.
Are You a Good Fit for This Trial?
Rules you outAutism spectrum disorderBipolar disorderSchizophreniaSubstance use disorders
You may be able to join if
I have been diagnosed with an anxiety disorder.
I do not use any psychotropic medication except for a stable dose of stimulant or SSRI.
I have a parent who is willing to participate.
You may not be able to join if
I am dealing with another mental health disorder that is more serious than my anxiety.
I have a history of suicide attempts or current suicidal thoughts.
I have been a victim of abuse that requires ongoing investigation.
I cannot speak and understand English well enough to participate.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
This study aims to test the efficacy of a parent-only approach to treating anxiety disorders in adolescents: SPACE (Supportive Parenting for Anxious Childhood Emotions). The comparator is another parent-based approach, PES (Parent Education and Support). The study design is a randomized controlled trial with 2 treatment arms and 3 assessment points (pre, post, and follow-up) using questionnaire da…
This study aims to test the efficacy of a parent-only approach to treating anxiety disorders in adolescents: SPACE (Supportive Parenting for Anxious Childhood Emotions). The comparator is another parent-based approach, PES (Parent Education and Support). The study design is a randomized controlled trial with 2 treatment arms and 3 assessment points (pre, post, and follow-up) using questionnaire data and clinical interviews.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Meet criteria for a primary DSM-5 AD, including separation anxiety disorder, social anxiety disorder, generalized anxiety disorder, specific phobia, panic disorder, and agoraphobia (determined by the ADIS-C/P).
* Cease all other psychosocial treatment, upon consultation with t…
Inclusion Criteria:
* Meet criteria for a primary DSM-5 AD, including separation anxiety disorder, social anxiety disorder, generalized anxiety disorder, specific phobia, panic disorder, and agoraphobia (determined by the ADIS-C/P).
* Cease all other psychosocial treatment, upon consultation with the project staff and service provider.
* Not currently use any psychotropic medication, other than a stable dose (i.e., same dose for a minimum of 6 months prior to enrollment; no changes during course of the study) of a stimulant medication or selective serotonin reuptake inhibitor (SSRI).
* Have an eligible and willing participating parent (see parent exclusions below).
Exclusion Criteria:
Adolescent:
* Meet criteria for any DSM-5 disorder more impairing than the most impairing AD (determined by the ADIS-C/P).
* Have any of the following disorders: autism spectrum disorder; intellectual disability; neurocognitive disorders; bipolar disorder; schizophrenia and other psychotic disorders; and alcohol and substance use disorders (determined by the Health History Form and ADIS-C/P).
* Report a suicide attempt in the last 3 months, or current suicide intent and plans (determined by the ASQ).
* Be a victim of past or present undisclosed abuse requiring investigation or ongoing supervision by the Department of Social Services.
* Not have sufficient proficiency with the English language to complete assessments.
Parents:
* Have any of the following: intellectual disability; neurocognitive disorders; untreated bipolar disorder; untreated schizophrenia and other psychotic disorders; and untreated alcohol and substance use disorders (determined by the Health History Form).
* Not be living with the adolescent at least 50% of the time for at least one year prior to enrollment.
* Not have sufficient proficiency with the English language to complete assessments and treatment.
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