Light Treatment for Alzheimer's Disease

Transcranial Photobiomodulation (tPBM) in Alzheimer's Disease Study

Recruiting N/A Interventional Study
Alzheimer's Disease
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
55 – 89
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
45 (estimated)
Sponsor
Cedars-Sinai Medical Center · Other
Who this trial is looking for

This trial is looking for people aged 55 to 89 with memory problems related to Alzheimer's disease. Participants will receive a special light treatment on their forehead and undergo cognitive tests and blood sample collection before and after the treatment.

Are You a Good Fit for This Trial?

You may be able to join if

  • I can attend in-person sessions at Cedars-Sinai every week.
  • I am between 55 and 89 years old.
  • I have been diagnosed with Mild Cognitive Impairment or mild dementia due to probable Alzheimer's disease.
  • I have signed an informed consent form.
  • I can comply with all study procedures.
  • I have been on a stable dose of Alzheimer's disease medications for at least 4 weeks, if applicable.

You may not be able to join if

  • I have a significant neurological condition other than Alzheimer's disease.
  • I have a history of seizures.
  • I have imaging results showing space-occupying lesions.
  • I have imaging with a Fazekas score greater than or equal to 3.
  • I am currently pregnant or breastfeeding.
  • I have participated in another clinical trial in the past 30 days.
  • I use illegal substances or non-prescribed psychoactive drugs.
  • I have severe dementia due to Alzheimer's disease or another cause.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.

Check Your Eligibility
About This Trial
The purpose of this study is to see if a special light treatment, called photobiomodulation, can help people with memory problems such as Mild Cognitive Impairment or Mild Dementia due to Alzheimer's disease. The light is given to the forehead using an FDA-cleared medical device. This device is cleared to provide topical heating to elevate tissue temperature for temporary relief of muscle and join…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Signed and dated informed consent form (either by subject or LAR) * Willingness and ability to comply with all study procedures * Age 55 to 89 years, inclusive * Clinical diagnosis of Mild Cognitive Impairment or mild dementia (CDR Global = 0-1; MoCA 16-25) due to probable Alz…
Contacts

Enrique Vargas Vargas, MD

972-281-7187

enrique.vargas@cshs.org

CONTACT

Golnaz Yadollahikhales, MD

310-385-6016

Golnaz.Yadollahikhales@cshs.org

CONTACT