No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 – 100
Sex
Any
Study type
Interventional
Purpose
Device Feasibility
Participants needed
15 (estimated)
Sponsor
University of Florida · Other
Who this trial is looking for
This trial is looking for adults with relapsing-remitting multiple sclerosis (MS) who have difficulty using their arms or hands. Participants will try a wearable device for 4 weeks to see if it helps improve their arm function.
Are You a Good Fit for This Trial?
You may be able to join if
I am over 18 years old.
I have been diagnosed with relapsing-remitting MS.
I have not had any MS relapses in the last 6 months.
I have reported problems with my arm or hand function.
I have been on my current MS treatment for at least 4 weeks.
I can use the FVT device after training.
I can speak English well enough to follow instructions.
I can visit the lab for assessments.
You may not be able to join if
I have cognitive impairment affecting my ability to follow instructions.
I have other neurological or psychiatric conditions affecting my arms.
I have unstable heart disease or a major medical issue.
I am pregnant or have conditions that make vibration therapy unsafe.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
This pilot mixed-method study will evaluate the feasibility, preliminary efficacy, and user experience of a home-based wearable Focal Vibration Therapy (FVT) intervention for improving upper extremity (UEx) function in people with multiple sclerosis (MS). Fifteen adults with relapsing-remitting MS (PRMS) and self-reported UEx impairments will participate in a 4-week FVT program using MyovoltTM wea…
This pilot mixed-method study will evaluate the feasibility, preliminary efficacy, and user experience of a home-based wearable Focal Vibration Therapy (FVT) intervention for improving upper extremity (UEx) function in people with multiple sclerosis (MS). Fifteen adults with relapsing-remitting MS (PRMS) and self-reported UEx impairments will participate in a 4-week FVT program using MyovoltTM wearable FVT devices applied to arm muscles.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Aged over 18 years
* Confirmed diagnosis of RRMS according to the McDonald criteria (33)
* No MS relapse or exacerbation within the past 6 months (ensuring stability of symptoms)
* Self-report on clinical evidence of UEx impairment (including reduced arm/hand function, muscle …
Inclusion Criteria:
* Aged over 18 years
* Confirmed diagnosis of RRMS according to the McDonald criteria (33)
* No MS relapse or exacerbation within the past 6 months (ensuring stability of symptoms)
* Self-report on clinical evidence of UEx impairment (including reduced arm/hand function, muscle weakness, spasticity, or pain).
* Stable on MS treatment for at least four weeks before recruitment, with no plans to initiate new treatments (participants may continue current treatments during the study)
* Agree and are able to use the FVT device after training.
* Sufficient proficiency in English to participate in interviews and follow instructions
* Able to visit the laboratory for assessments
* Able to provide written informed consent
Exclusion Criteria:
* Evidence of cognitive impairment that could interfere with following instructions (Mini-Montreal Cognitive Assessment score (Mini-MoCA) \< 12)
* Comorbid neurological or psychiatric conditions affecting the UEx (including stroke and severe carpal tunnel syndrome) that would confound results or make FVT unsafe
* Unstable cardiac disease or any major medical illness that would preclude participation
* Any known contraindications to vibration therapy (pregnancy, acute deep vein thrombosis, severe osteoporosis, chronic migraines, epilepsy, active malignancy in the target area, unstable cardiac disease, or an implanted pacemaker without clearance)
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