Non-invasive Vagus Nerve Stimulation to Reduce Inflammation and Brain Injury Blood Biomarkers Following an Acute Ischemic Stroke
Recruiting
N/A
Interventional Study
Large Vessel Occlusion
Acute Ischemic Stroke
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 – 99
- Sex
- Any
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 65 (estimated)
- Sponsor
- Washington University School of Medicine · Other
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About This Trial
This is a randomized open-label, with blinded outcome pilot study to evaluate the effect on inflammatory and brain injury laboratory values and explore clinical outcomes in patients who present with ischemic strokes due to large vessel occlusions and are treated with either current accepted management, or accepted management in addition to transcutaneous auricular vagal nerve stimulation.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Adult patients who present with acute ischemic strokes due to large vessel occlusions
Exclusion Criteria:
* \<18 years old
* patients with presumed chronic large vessel occlusions
* NIHSS\<6
* pre-morbid modified Rankin score (mRS) \>2
* unable to initiate treatment under 24…
Contacts