Inhaled Corticosteroids for Asthma Study

Ventilation and Perfusion in Asthmatics

Recruiting Phase 4 Interventional Study
Asthma
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 – 75
Sex
Any
Trial phase
Phase 4
Study type
Interventional
Purpose
Treatment
Participants needed
40 (estimated)
Sponsor
University of Miami · Other
Who this trial is looking for

This trial is looking for adults with asthma who are currently using inhaled corticosteroids. Participants will undergo tests to measure how well their lungs are working after using specific asthma medications.

Are You a Good Fit for This Trial?
Must be taking Inhaled corticosteroids

You may be able to join if

  • I have been diagnosed with asthma
  • I am between 18 and 75 years old
  • I have mild to moderate asthma symptoms
  • I have been using inhaled corticosteroids for at least 3 months
  • My lung function test shows FEV1 less than 80% of predicted
  • I have a 10% improvement in FEV1 after using a bronchodilator

You may not be able to join if

  • I am currently smoking or have smoked more than 10 pack-years in the past
  • I am currently vaping nicotine
  • I am pregnant or breastfeeding
  • I have had a respiratory infection in the last 4 weeks
  • My FEV1 is less than 50%
  • I cannot tolerate inhaled corticosteroids or fast-acting beta agonists
  • I am taking beta-blockers
  • I have used glucocorticosteroids or oral methyl-xanthines in the last 30 days

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer a few quick questions to see if you may meet the eligibility requirements.

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About This Trial

Assess regional changes to perfusion and ventilation from inhaled corticosteroid (ICS) and Fast-acting beta-antagonist (FABA) among adult asthmatics using radiographically derived estimates of regional ventilation (V-distribution), ventilation defect percentage (VDP), and ventilation heterogeneity (VH).

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Physician diagnosis of asthma * Baseline Forced Expiratory Volume in 1 Second (FEV1) \< 80% of predicted, with reversibility (10%) on post-bronchodilator spirometry * Adults, 18-75 years of age * Long-term inhaled controller medication consisting of or including an Inhaled cor…
Contacts

Maria McCoy

305-243-2568

mcm456@med.miami.edu

CONTACT

Sonia Dipti Meena Velmurugan, MS

305-243-2568

sxm3597@med.miami.edu

CONTACT