Investigating Subcortical Contributions to Speech Sequencing in Deep Brain Stimulator Recipients

Recruiting N/A Interventional Study
Parkinson's Disease (PD) Essential Tremor
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Basic Science
Participants needed
80 (estimated)
Sponsor
Boston University Charles River Campus · Other
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About This Trial
This study will examine how two important brain circuits - one involving the subthalamic nucleus (STN) and one involving the ventral intermediate nucleus of the thalamus (VIM) - contribute to learning and producing speech sequences. Participants will include two groups: 1. individuals with Parkinson's disease who have deep brain stimulation (DBS) devices targeting the STN and 2. individuals with e…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Native speakers of American English * Adults at least 18 years of age * A clinically established diagnosis of Parkinson's disease or essential tremor * Able to provide informed consent in the judgment of the investigator * Treated with deep brain stimulation of the subthalamic…
Contacts

Frank H Guenther, Ph.D.

617-353-5765

guenther@bu.edu

CONTACT

Barbara G Holland, MA

617-353-6181

bobbieh@bu.edu

CONTACT