No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
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Review the details below, then apply to join this clinical trial.
At a Glance
Age
30 – 80
Sex
Any
Study type
Interventional
Purpose
Diagnostic
Participants needed
18 (estimated)
Sponsor
University of Cincinnati · Other
Who this trial is looking for
This trial is looking for people who have walking difficulties due to a stroke. Participants will take part in walking tests on a treadmill to help researchers understand walking efficiency and energy costs.
Are You a Good Fit for This Trial?
You may be able to join if
I am between 30 and 80 years old.
I have had a stroke that caused weakness on one side of my body.
My most recent stroke was at least 3 months ago.
I walk slower than 1.0 m/s in a 10-meter walk test.
I can walk 10 meters using assistive devices if needed.
I can walk continuously for at least 5 minutes on a treadmill.
You may not be able to join if
I was hospitalized for heart or lung issues in the past 3 months.
I have a pacemaker or defibrillator implanted.
I have severe tightness in my leg muscles.
I have foot drop or unstable joints without proper support.
I have a significant neurological disorder besides stroke.
I have other serious health issues that could make participation unsafe.
I am pregnant.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
Walking impairment following neurologic injury can increase the energy cost of walking threefold, acting as a functional barrier to independence. The goal of this cross-sectional study is to determine the measurement properties of a novel biomechanical cost of walking measure in chronic stroke capable of pinpointing the origins of movement inefficiencies. This research aims to:
1. determine the c…
Walking impairment following neurologic injury can increase the energy cost of walking threefold, acting as a functional barrier to independence. The goal of this cross-sectional study is to determine the measurement properties of a novel biomechanical cost of walking measure in chronic stroke capable of pinpointing the origins of movement inefficiencies. This research aims to:
1. determine the convergent validity of biomechanical cost of walking with functional measures in relation to metabolic cost of walking,
2. determine the reliability of biomechanical cost of walking in relation to metabolic cost of walking,
3. determine the responsiveness of biomechanical cost of walking in relation to metabolic cost of walking.
Individuals with walking impairment from stroke will complete three 5-minute comfortable speed treadmill walking trials. The 3rd walking trial will be against resistance to increase cost of walking. This single session study will compare the metric properties of biomechanical cost of walking in relation to metabolic cost of walking.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Age 30-80 years at the time of consent
* Hemiparesis from ischemic and/or hemorrhagic strokes
* Most recent stroke for which participant sought treatment, at least 3 months prior to study consent
* Walking speed \<1.0 m/s on the 10-meter walk test
* Able to walk 10m over groun…
Inclusion Criteria:
* Age 30-80 years at the time of consent
* Hemiparesis from ischemic and/or hemorrhagic strokes
* Most recent stroke for which participant sought treatment, at least 3 months prior to study consent
* Walking speed \<1.0 m/s on the 10-meter walk test
* Able to walk 10m over ground with assistive devices as needed
* Able to walk at least 5 minutes continuously on the treadmill ≥ 0.1 mile per hour
* No contraindications to exercise according to ACSM guidelines
* Able to communicate with investigators, follow a 2-step command and correctly answer consent comprehension questions
Exclusion Criteria:
* Hospitalization for cardiac or pulmonary disease within past 3 months
* Implanted pacemaker or defibrillator
* Severe lower limb hypertonia (Ashworth \>2)
* Foot drop or lower limb joint instability without adequate stabilizing device
* Clinically significant neurologic disorder other than stroke
* Other significant medical condition likely to jeopardize safety (e.g. joint contracture, gait limited by pain)
* Pregnancy
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