Prednisone Use for Pain Relief After Hip or Knee Surgery

Post-op Prednisone and Glucose Monitoring in TKA

Recruiting Phase 4 Interventional Study
Osteoarthritis Unicompartmental Knee Arthroplasty Total Hip Arthroplasty (THA)
Prior Safety Data This treatment has already been tested in at least one earlier human trial.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 and older
Sex
Any
Trial phase
Phase 4
Study type
Interventional
Purpose
Treatment
Participants needed
104 (estimated)
Sponsor
Columbia University · Other
Who this trial is looking for

This trial is looking for people having knee or hip surgery. Participants will receive a medication for five days after their surgery and will have their pain and glucose levels monitored.

Are You a Good Fit for This Trial?

You may be able to join if

  • I am having a total hip or unicompartmental knee surgery
  • I am 18 years old or older

You may not be able to join if

  • I am currently taking steroids
  • I have used narcotics in the past 3 months
  • I have a history of not tolerating corticosteroids
  • I am pregnant
  • I have uncontrolled diabetes
  • I do not own a smart phone

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

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About This Trial

This study compares the efficacy of a 5-day post-operative oral prednisone regimen (40 mg daily) with the standard intraoperative steroid regimen, focusing on pain, swelling, range of motion, opioid use, and glucose levels monitored continuously.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * MUST BE CONTACTED BY THE STUDY TEAM TO BE PART OF THE STUDY. No applications taken * Undergoing Primary Unicompartmental Knee Arthroplasty or Total Hip Arthroplasty * Age 18 and above * Patient at Columbia University Irving Medical Center and be undergoing planned surgery by D…
Contacts

Jacqueline Lenahan

(212) 305-8193

jl5092@cumc.columbia.edu

CONTACT