No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
152 (estimated)
Sponsor
Duke University · Other
Who this trial is looking for
This trial is looking for adults with high blood pressure and advanced chronic kidney disease. Participants will either learn about kidney health or join a program that includes healthy eating, exercise, and wellness coaching over 12 weeks.
I agree to be randomly assigned to one of the two groups.
You may not be able to join if
I am currently on dialysis or need a kidney transplant.
I have had an acute kidney injury recently.
My blood pressure is very high.
I have a severe heart condition.
I have severe asthma or lung disease.
I have a major psychiatric disorder.
I am pregnant or plan to become pregnant soon.
I have had gastric bypass surgery in the last 2 years.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
This research study will test whether a 12-week healthy lifestyle program offered through a cardiac rehabilitation center can help lower blood pressure and improve kidney health in adults with advanced chronic kidney disease. Participants will be randomly assigned to either routine kidney health education or take part in a program that includes healthy eating guidance, supervised exercise sessions…
This research study will test whether a 12-week healthy lifestyle program offered through a cardiac rehabilitation center can help lower blood pressure and improve kidney health in adults with advanced chronic kidney disease. Participants will be randomly assigned to either routine kidney health education or take part in a program that includes healthy eating guidance, supervised exercise sessions, and wellness coaching. The goal of the study is to determine whether this program can improve blood pressure and other factors linked to worsening kidney disease.
Trial Locations
Loading…
Loading trial locations…
Facility
City
State
Country
Status
Eligibility Criteria
Inclusion Criteria:
* Black race; ≥18 years old
* history of hypertension
* SBP ≥120 or DBP ≥80 mm Hg average of three measurements at screening visit (per KDIGO recommended SBP target of \<120 mm Hg)48
* Stable anti-hypertensive medication regimen (i.e., no medication changes 4 weeks prior to enro…
Inclusion Criteria:
* Black race; ≥18 years old
* history of hypertension
* SBP ≥120 or DBP ≥80 mm Hg average of three measurements at screening visit (per KDIGO recommended SBP target of \<120 mm Hg)48
* Stable anti-hypertensive medication regimen (i.e., no medication changes 4 weeks prior to enrollment);
* eGFR of 15-44 ml/min/1.73m2 at screening visit
* agreeable to randomization to either of the 2 study arms
Exclusion Criteria:
* currently receiving or needing dialysis; having received or needing a kidney transplant
* acute kidney injury at time of screening
* average SBP ≥ 180 mm Hg or DBP ≥ 110 mm Hg at screening
* Exaggerated systolic response during ETT (e.g., SBP \>210 mmHg in men or \>190 mmHg in women)
* underweight (BMI \<18.5 kg/m2)
* planned weight loss surgery in 1 year
* a score of 27 or higher on the BP medication adherence scale
* cardiac condition that would preclude participation in aerobic exercise training, including severe ischemic heart disease (CCS Class 3 or 4 angina or evidence of ischemia at \<85% heart rate reserve on screening treadmill testing), severe heart failure (NYHA Class 3 or 4), high grade arrhythmias, severe valvular heart disease
* severe asthma or chronic obstructive lung disease
* musculoskeletal or neurologic conditions that would preclude participation in aerobic exercise training
* a major psychiatric disorder
* illicit drug abuse
* current alcohol consumption \>14 drinks/week for men and \>7 drinks/week for women
* pregnant or planned pregnancy within 1 year
* gastric bypass surgery within the last 2 years
* a life-limiting comorbid medical condition, such as cancer.
* physical limitation, gait instability, or need for continuous weight-bearing support that, in the opinion of study staff, would prevent safe completion of exercise treadmill testing
Picking one helps us show the most relevant trials first.
Your results are loading in the background — you can
change this any time from the results page.
Set your location to continue
Find My Trials uses your location to surface clinical trials near you.
Add your city or zip code to your profile and try again.