tDCS Therapy for Late-Life Depression
tDCS for Late-Life Depression
Recruiting
Phase 1
Phase 2
Interventional Study
Late Life Depression (LLD)
Depression - Major Depressive Disorder
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 60 and older
- Sex
- Any
- Trial phase
- Phase 1/2
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 20 (estimated)
- Sponsor
- Andre Russowsky Brunoni · Other
Who this trial is looking for
This trial is looking for older adults aged 60 and over who are experiencing late-life depression. Participants will receive a treatment involving a non-invasive brain stimulation method delivered three times a week for three weeks.
Are You a Good Fit for This Trial?
You may be able to join if
- I am 60 years old or older.
- I have been diagnosed with major depressive disorder.
- I have a score of 16 or higher on a depression rating scale.
- I have been on a stable antidepressant for at least four weeks, if applicable.
- I can give my consent to participate.
- I have a Clinical Dementia Rating of 0 or 0.5.
- I have someone who knows about my daily functioning.
You may not be able to join if
- I have metal implants in my head.
- I have skin problems at the stimulation sites.
- I have a history of seizures or epilepsy.
- I have bipolar disorder.
- I have active suicidal thoughts or a plan.
- I have a history of substance use disorder in the past six months.
- I am currently pregnant.
- I am considered medically unstable by the doctors.
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
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About This Trial
The purpose of this research study is to determine the effectiveness of Transcranial direct current stimulation (tDCS) therapy in the treatment of participants with Late-life depression (LLD).
The study will evaluate feasibility, safety, and tolerability of high-dose (6mA) bilateral tDCS delivered as three daily sessions, 3 times a week, for 3 weeks in older adults (60 y/o and older) with late-li…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
Participants must meet all of the following criteria:
1. age 60 years or older;
2. diagnosis of unipolar major depressive disorder according to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5), confirmed by the Structured Clinical Interview for D…
Contacts