Breathing Treatment for Parkinsonism Symptoms
Cross-System Effects of Acute Intermittent Hypercapnia-Based Interventions in PD
Recruiting
N/A
Interventional Study
Parkinson Disease
Parkinsonism
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 40 – 75
- Sex
- Any
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 32 (estimated)
- Sponsor
- University of Florida · Other
Who this trial is looking for
This trial is looking for adults with Parkinsonism to test if a special breathing treatment can help improve their breathing and movement. Participants will try one session of this treatment and share how it affects them.
Are You a Good Fit for This Trial?
You may be able to join if
- I am between 40 and 75 years old.
- I have been diagnosed with Parkinsonism.
- I can walk at least 10 feet with or without help.
- I can follow directions.
- I am medically stable with my doctor's approval.
- I am willing to not donate blood during the study.
You may not be able to join if
- I have other neurological conditions.
- I have a severe illness or infection.
- I have pregnancy or might be pregnant.
- I smoke cigarettes or vape.
- I have had head, neck, or lung cancer (except basal cell carcinoma).
- I am in another research study that might affect this one.
- I have deep brain stimulation electrodes or a history of this treatment.
- I faint or feel lightheaded at the sight of blood.
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
Check Your Eligibility
About This Trial
Parkinsonism impairs upper airway and axial motor control, leading to disordered breathing, reduced speech volume, and ineffective cough. Symptoms are poorly addressed by current therapies. This randomized pilot trial tests whether a single session of acute intermittent hypercapnic hypoxia (AIHH) or hypercapnic normoxia (AIHN) improves upper airway and axial motor function in Parkinsonism, and exp…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
1. adults 40 to 75 years of age (the latter to reduce the likelihood of cardiovascular disease)
2. diagnosis of idiopathic Parkinsonism with Hoehn and Yahr stages 2-4
3. medically stable with physician clearance
4. ability to ambulate at least 10 feet with/without assistance
5. …
Contacts