Topical-Lingual Semaglutide for Obesity

A Proof-of-Concept Study to Evaluate Topical-Lingual Semaglutide in Adults With Obesity

Recruiting Phase 4 Interventional Study
Obesity & Overweight
Prior Safety Data This treatment has already been tested in at least one earlier human trial.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 – 65
Sex
Any
Trial phase
Phase 4
Study type
Interventional
Purpose
Treatment
Participants needed
40 (estimated)
Sponsor
Gila Therapeutics, Inc. · Industry
Who this trial is looking for

This trial is looking for adults with obesity who want to try a new way to take a medication that might help with weight management. Participants will take a special liquid form of the drug semaglutide to see if it can help reduce weight.

Are You a Good Fit for This Trial?

You may be able to join if

  • I have a Body Mass Index (BMI) between 30 and 45.

You may not be able to join if

  • I have type 2 diabetes.
  • I have Multiple Endocrine Neoplasia Type 2.
  • I have had medullary thyroid cancer.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

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About This Trial

This study investigates the Topical-Lingual (T-L) delivery of semaglutide, a GLP-1 receptor agonist (GLP-1RA), via an oral liquid emulsion formulation as a Proof-of-Concept for the T-L delivery of metabolic hormones in general. GLP-1 is a gut-derived hormone that induces satiation through hypothalamic pathways.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Body Mass Index 30 to 45 Exclusion Criteria: * Type 2 Diabetes Mellitus * Multiple Endocrine Neoplasia Type 2 * Medullary thyroid cancer
Contacts

No contact information available.