A Proof-of-Concept Study to Evaluate Topical-Lingual Semaglutide in Adults With Obesity
Recruiting
Phase 4
Interventional Study
Obesity & Overweight
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About This Trial
This study investigates the Topical-Lingual (T-L) delivery of semaglutide, a GLP-1 receptor agonist (GLP-1RA), via an oral liquid emulsion formulation as a Proof-of-Concept for the T-L delivery of metabolic hormones in general. GLP-1 is a gut-derived hormone that induces satiation through hypothalamic pathways.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Body Mass Index 30 to 45
Exclusion Criteria:
* Type 2 Diabetes Mellitus
* Multiple Endocrine Neoplasia Type 2
* Medullary thyroid cancer
Contacts
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