Microbiome Study for Cognitive Health and Aging
Microbiome in Aging of Gut and Brain
Recruiting
Observational Study
Mild Cognitive Impairment
Alzheimer Disease (AD)
Dementia
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Observational
- Participants needed
- 700 (estimated)
- Sponsor
- University of South Florida · Other
Who this trial is looking for
This trial is looking for adults to examine how gut and mouth microorganisms relate to thinking and memory. Participants will provide samples and complete assessments, with some followed for up to 5 years.
Are You a Good Fit for This Trial?
You may be able to join if
- I am between 18 and 60 years old or 60 years and older.
- I have normal cognitive function or mild cognitive impairment or Alzheimer's disease.
- I am able to participate in the informed consent process.
- If I can't provide consent, a legally authorized representative can do so.
You may not be able to join if
- I have had brain or gastrointestinal surgery in the past 5 years.
- I have had cancer or cancer treatment in the past 5 years, except non-melanoma skin cancer.
- I have a neurological disorder like epilepsy or Parkinson's disease.
- I have taken antibiotics in the past 30 days.
- I have had diarrhea, vomiting, or food poisoning in the past 30 days.
- I have a history of inflammatory bowel disease.
- My body mass index (BMI) is greater than 45 or less than 18.
- I have lost more than 10 pounds in the past 2 weeks.
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
Check Your Eligibility
About This Trial
The Microbiome in Aging Gut and Brain (MiaGB) Study is an observational study designed to examine whether differences in the microorganisms living in the gut and mouth are associated with cognitive health and cognitive decline.
The study includes young healthy adults, cognitively healthy older adults, older adults with mild cognitive impairment (MCI), and older adults with Alzheimer's disease or …
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Age 18-60 years for young healthy participants, or age 60 years and older for older adult participants.
* Participants meeting one of the following cognitive categories:
* Normal cognitive function
* Mild cognitive impairment (MCI)
* Alzheimer's disease or Alzheimer's disease-…
Contacts