Messages to Help Increase COVID-19 Vaccination

Effect of Messaging on Pragmatic Outcomes Within an Integrated Healthcare System

Recruiting N/A Interventional Study
Covid-19 Vaccination
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Healthy Volunteers Welcome You do not need to have the condition being studied to take part.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Health Services Research
Participants needed
1,300,000 (estimated)
Sponsor
Kaiser Permanente · Other
Who this trial is looking for

This trial is looking for adults who are at high risk for severe COVID-19 illness. Participants will receive messages and reminders about COVID-19 vaccine options to see if it helps them get vaccinated.

Are You a Good Fit for This Trial?

You may be able to join if

  • I am at least 18 years old.
  • I am a member of Kaiser Permanente Southern California.
  • I have been a member continuously since August 27, 2025.
  • I have not received the updated COVID-19 vaccine by September 28, 2026.
  • I am 65 years old or older or have certain health conditions that increase my risk for severe COVID-19.

You may not be able to join if

  • I cannot receive a COVID-19 vaccine safely.
  • I have a severe allergic reaction to a previous COVID-19 vaccine.
  • I have a terminal illness or I am receiving hospice care.
  • I am pregnant or breastfeeding.
  • I have missing or unknown sex.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.

Check Your Eligibility
About This Trial
COVID-19 vaccination among patients at high risk for severe disease has declined in the United States since 2022. Prior research, including discrete choice experiments (DCEs), has demonstrated that vaccine preferences are influenced by attributes such as effectiveness, safety, convenience, and protection against severe disease. Although DCEs provide valuable insights into stated vaccine preference…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Aged ≥18 years; * Active KPSC member; * Continuous membership from 27 August 2025 to 28 September 2026; * Members who are aged 65 years and older, or adults aged 18-64 years with at least one of the following health conditions that increases their risk for severe COVID-19 illn…
Contacts

Annette Regan, PhD

626-760-2482

annette.k.regan@kp.org

CONTACT

Zendi S Yha, BS

626-372-5637

zendi.s.yha@kp.org

CONTACT