Understanding Brain Responses to Fear and Anxiety
Intracranial Neurophysiological Signatures of Fear and Anxiety in Humans
Recruiting
N/A
Interventional Study
Fear
GAD
Emotional Memory
PTSD
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 18 – 70
- Sex
- Any
- Study type
- Interventional
- Purpose
- Basic Science
- Participants needed
- 80 (estimated)
- Sponsor
- Duke University · Other
Who this trial is looking for
This trial is looking for adults who have received neurostimulation treatment and want to help us understand how fear and anxiety work in the brain. Participants will complete tasks on a computer and in virtual reality while we measure their brain activity, heart rate, and skin sweat.
Are You a Good Fit for This Trial?
You may be able to join if
- I am 18 years of age or older
- I have had neurostimulation electrode placement
- I am willing to provide informed consent
- I can read and write English fluently
You may not be able to join if
- I am unwilling to provide informed consent
- I have not had neurostimulation electrode placement
- I am pregnant
- I have active psychosis
- I have suicidal thoughts
- I have substance abuse issues
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
Check Your Eligibility
About This Trial
Anxiety disorders such as post-traumatic stress disorder (PTSD) and generalized anxiety disorder (GAD) affect a large number of individuals with a significant portion of patients failing to improve with current treatments.
The purpose of this study is to understand the brain mechanisms that produce fear and anxiety in humans. To accomplish this goal, we will measure the brain activity along with …
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* 18 years of age or older
* Has undergone acute depth or chronic responsive neurostimulation (RNS) electrode placement
* Willing to provide informed consent and participate in the study
* Ability to read and write English fluently
Exclusion Criteria:
* Unwilling to provide in…
Contacts