No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
3 and older
Sex
Any
Study type
Observational
Participants needed
20,000 (estimated)
Sponsor
National Institute of Allergy and Infectious Diseases (NIAID) · NIH
Who this trial is looking for
This trial is looking for people aged 3 and older who have or may have a respiratory virus infection. Participants will provide blood and nose samples to help researchers learn more about respiratory viruses.
Are You a Good Fit for This Trial?
You may be able to join if
I am 3 years old or older.
I have been diagnosed with a respiratory virus or am suspected to have one.
I am willing to follow all study procedures during the trial.
You may not be able to join if
I have a medical condition that would make it unsafe for me to participate.
I do not speak English and am unable to have an interpreter present.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
Background:
Respiratory viruses, like the flu or COVID-19, cause significant illness and death worldwide. Researchers want to collect samples from people with respiratory virus infections. The samples in this natural history study will be used in future research.
Objective:
To obtain samples from people with respiratory viruses to learn more about respiratory virus infections and the immune res…
Background:
Respiratory viruses, like the flu or COVID-19, cause significant illness and death worldwide. Researchers want to collect samples from people with respiratory virus infections. The samples in this natural history study will be used in future research.
Objective:
To obtain samples from people with respiratory viruses to learn more about respiratory virus infections and the immune responses against them.
Eligibility:
People aged 3 and older who have or are suspected to have a respiratory virus infection.
Design:
Participants will be screened with a medical record review.
Participants will give blood samples. Data from their medical records will be collected.
Participants will give nose samples. A soft plastic strip will be put into each nostril for a minute. They may also give nose, mouth (back of the throat), or saliva samples using swabs.
Participants may receive kits by mail to collect nose and blood samples at home. They will use soft plastic strips to collect nose samples. To collect blood, they will prick their finger and dab a few drops of blood on four plastic tips.
If a participant is in the hospital, air samples may be collected in their room.
Participation will last for up to 2 years. After 2 years, participants may be asked for their consent again to give new samples and new medical data.
Trial Locations
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Facility
City
State
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Status
Eligibility Criteria
* INCLUSION CRITERIA:
In order to be eligible to participate in this study, an individual must meet all of the following criteria:
1. Aged 3 years or older.
2. Documented or suspected infection with a respiratory virus.
3. Stated willingness to comply with all study procedures for the duration of …
* INCLUSION CRITERIA:
In order to be eligible to participate in this study, an individual must meet all of the following criteria:
1. Aged 3 years or older.
2. Documented or suspected infection with a respiratory virus.
3. Stated willingness to comply with all study procedures for the duration of the study.
EXCLUSION CRITERIA:
An individual who meets any of the following criteria will be excluded from participation in this study:
1\. Any condition that, in the opinion of the investigator, would compromise the safety of the study participant or staff, or would prevent proper conduct of the study.
Non-English Speaking Participants: This study will enroll non-English speaking participants.
For non-English speaking participants, the study will be explained to the participant/family through an interpreter, in the presence of the study team, in the language understood by the participant/family. The short form in the language understood by the participant/family will be signed by the participant/family or LAR and the interpreter, and the consent will be signed by the consenting provider and the interpreter.
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