Decoding and Modulating Affective Brain States

Recruiting N/A Interventional Study
Rumination Major Depressive Disorder Anxiety
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 – 65
Sex
Any
Study type
Interventional
Purpose
Basic Science
Participants needed
40 (estimated)
Sponsor
University of Pennsylvania · Other
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About This Trial
The research study is being conducted to study brain patterns of negative emotion and develop personalized brain stimulation protocols to disrupt these patterns with transcranial magnetic stimulation (TMS). First, the investigators will use functional Magnetic Resonance Imaging (fMRI) data to generate a negative affect map for each participant. Then, the investigators will apply a variety of repet…
Trial Locations
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Eligibility Criteria
Inclusion criteria: 1. 18-65 years old 2. Patient Health Questionnaire (PHQ-9 score) = or \> than 10 3. Comprehension of instructions in the English language. 4. Capacity to provide informed consent and follow study procedures. 5. Availability for the duration of the study. Exclusion Criteria: 1.…
Contacts

Camille Blaine

215-573-0828

camille.blaine@pennmedicine.upenn.edu

CONTACT

Almaris Figueroa-Gonzalez

215-746-6751

almaris.figueroa-gonzalez@pennmedicine.upenn.edu

CONTACT