Decoding and Modulating Affective Brain States
Recruiting
N/A
Interventional Study
Rumination
Major Depressive Disorder
Anxiety
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 – 65
- Sex
- Any
- Study type
- Interventional
- Purpose
- Basic Science
- Participants needed
- 40 (estimated)
- Sponsor
- University of Pennsylvania · Other
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About This Trial
The research study is being conducted to study brain patterns of negative emotion and develop personalized brain stimulation protocols to disrupt these patterns with transcranial magnetic stimulation (TMS). First, the investigators will use functional Magnetic Resonance Imaging (fMRI) data to generate a negative affect map for each participant. Then, the investigators will apply a variety of repet…
Trial Locations
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Eligibility Criteria
Inclusion criteria:
1. 18-65 years old
2. Patient Health Questionnaire (PHQ-9 score) = or \> than 10
3. Comprehension of instructions in the English language.
4. Capacity to provide informed consent and follow study procedures.
5. Availability for the duration of the study.
Exclusion Criteria:
1.…
Contacts