No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
13 – 17
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
82 (estimated)
Sponsor
Vanderbilt University · Other
Who this trial is looking for
This trial is looking for young people aged 13 to 17 who are experiencing depression. Participants will receive either standard therapy or enhanced therapy that focuses on improving social skills.
Are You a Good Fit for This Trial?
You may be able to join if
I am between 13 and 17 years old
I have a current diagnosis of depression
I have a score greater than 15 on the Patient Health Questionnaire
You may not be able to join if
I have been diagnosed with bipolar disorder, schizophrenia, autism, or conduct disorder
I have a current alcohol or substance use disorder
I am at imminent risk of suicide
I have a reading level below 4th grade
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
Depression in youth is a serious public health concern for which more personalized treatments are needed. This randomized controlled trial will test the effect of an intervention aimed at enhancing social cognitive capacities (e.g., ability to take another's perspective), thereby making treatment of depression in youth more efficient and effective. Participants in the R33 (N=82) will be youth betw…
Depression in youth is a serious public health concern for which more personalized treatments are needed. This randomized controlled trial will test the effect of an intervention aimed at enhancing social cognitive capacities (e.g., ability to take another's perspective), thereby making treatment of depression in youth more efficient and effective. Participants in the R33 (N=82) will be youth between ages 13- through 17-years-old currently experiencing depression. Youth will be randomized to either an enhanced CBT intervention that teaches social cognitive skills, particularly social perspective taking and theory of mind (CBTSCT) as compared to CBT only. The primary target is improvement in both social cognitive skills and depressive symptoms at post-treatment and at a 6-month follow-up.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
1. Participants ages 13- through 17-years-old
2. Youth must have a diagnosis of a current depressive disorder (e.g., major depressive episode; persistent depressive disorder) or a score on the Patient Health Questionnaire (PHQ9) \> 15
Exclusion Criteria:
* ever met criteria fo…
Inclusion Criteria:
1. Participants ages 13- through 17-years-old
2. Youth must have a diagnosis of a current depressive disorder (e.g., major depressive episode; persistent depressive disorder) or a score on the Patient Health Questionnaire (PHQ9) \> 15
Exclusion Criteria:
* ever met criteria for a diagnosis of bipolar disorder, schizophrenia, autism, or conduct disorder
* current alcohol or substance use disorder with significant impairment
* imminent risk of suicide
* reading level \< 4th grade
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