Behavioral Activation Therapy for Depression

Mechanisms of Behavioral Activation (BA)

Recruiting N/A Interventional Study
Depression
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Healthy Volunteers Welcome You do not need to have the condition being studied to take part.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
15 – 17
Sex
Any
Study type
Interventional
Purpose
Other
Participants needed
136 (estimated)
Sponsor
Emory University · Other
Who this trial is looking for

This trial is looking for adolescents with depression who are aged 15-17. Participants will undergo brain scans before, during, and after treatment with Behavioral Activation therapy to study how their brain responds.

Are You a Good Fit for This Trial?
Must not be taking Psychotropic medications
Rules you out Bipolar disorderSchizophreniaPsychosisAnorexiaOCDAutism spectrum disorders

You may be able to join if

  • I am 15-17 years old.
  • I have been diagnosed with major depressive disorder (MDD).
  • I have a CDRS-R score above 45.
  • I can provide treatment as an outpatient.
  • I have a full-scale IQ above 80.
  • I have access to a smartphone, tablet, or computer.
  • I am not taking any other psychosocial treatments.

You may not be able to join if

  • I have a current or past diagnosis of bipolar disorder or schizophrenia.
  • I have a current diagnosis of a severe developmental disorder or OCD.
  • I am currently taking psychotropic medications.
  • My estimated IQ is below 80.
  • I have had alcohol or drug dependence in the last 3 months.
  • I have a history of serious seizures or neurological disorders.
  • I am pregnant.
  • I have had a traumatic brain injury.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.

Check Your Eligibility
About This Trial
The investigators will be comparing brain (neural) activation of depressed adolescent patients before, during and after a course of Behavioral Activation (BA) therapy using functional magnetic resonance imaging (fMRI). In particular, the project seeks to determine whether BA targets different neural mechanisms for behavioral avoidance associated with low motivation as compared to threat avoidance.…
Trial Locations
Loading…

Loading trial locations…

Eligibility Criteria
Inclusion Criteria: * Male and female adolescents ages 15-17; * current MDD diagnosis as determined by K-SADS-PL, * CDRS-R raw score \> 45 (T-score \> 65) at baseline; * estimated full scale IQ \> 80 as determined by the WASI-II; * able to receive outpatient care; * willing to not partake in other …
Contacts

Wade E Craighead, PhD

4047273287

ecraigh@emory.edu

CONTACT

Michael Treadway, PhD

mtreadway@emory.edu

CONTACT