Weight Loss Program for Obese Veterans with Post-COVID Symptoms
Modifying Adiposity Through Behavioral Strategies to Improve COVID-19 Rehabilitation
Recruiting
N/AInterventional Study
Post-COVID ConditionsObesity
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
Up to 80
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
150 (estimated)
Sponsor
VA Office of Research and Development · Federal
Who this trial is looking for
This trial is looking for U.S. Veterans who are obese and have experienced COVID-19 symptoms for at least 4 weeks. Participants will follow a weight loss program that includes diet changes and exercise to see if it helps improve their health and recovery.
Are You a Good Fit for This Trial?
You may be able to join if
I am a U.S. Veteran
I have had COVID-19 more than 90 days ago or I have symptoms for over 4 weeks
My Body Mass Index is between 30 and 50 kg/m2
You may not be able to join if
I have a condition that limits my ability to participate in physical activities
I have an active illness, including COVID-19 or any serious infectious disease
I have uncontrolled diabetes or use insulin
I have lost more than 5 kg in the past month
I have a history of alcohol or drug abuse
I am taking anti-coagulant medication
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
The research in this VA Merit will examine the effects of obesity and Post-COVID Conditions (PCC) on physical functioning, health-related quality of life, and adipose tissue inflammatory and cellular senescence profiles in older Veterans. Further, it will evaluate whether a weight loss intervention, including dietary modification and exercise, in obese Veterans with and without PCC will reduce sys…
The research in this VA Merit will examine the effects of obesity and Post-COVID Conditions (PCC) on physical functioning, health-related quality of life, and adipose tissue inflammatory and cellular senescence profiles in older Veterans. Further, it will evaluate whether a weight loss intervention, including dietary modification and exercise, in obese Veterans with and without PCC will reduce systemic and adipose tissue inflammation and senescence and promote PCC recovery.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
1. U.S. Veteran
2. Self-reported COVID-19 naïve or COVID-19 \> 90 days ago for lean and obese PCC naïve or documented COVID-19 for the lean and obese PCC groups (At least one PCC symptom \>4 weeks)
3. Body Mass Index: 19-25 or 30-50 kg/m2
Exclusion Criteria:
1. Neurologic, mus…
Inclusion Criteria:
1. U.S. Veteran
2. Self-reported COVID-19 naïve or COVID-19 \> 90 days ago for lean and obese PCC naïve or documented COVID-19 for the lean and obese PCC groups (At least one PCC symptom \>4 weeks)
3. Body Mass Index: 19-25 or 30-50 kg/m2
Exclusion Criteria:
1. Neurologic, musculoskeletal, or other condition that limits subject's ability to complete study physical assessments
2. Active inflammatory, COVID-19, autoimmune, infectious, hepatic (LFTs \> 2.5 x WNL), renal (eGFR\<45), gastrointestinal, malignant, and psychiatric disease
3. Uncontrolled diabetes (HbA1c \>10% or the current use of insulin)
4. Weight change within the past month of \>5 kg
5. Self-reported alcohol or drug abuse
6. Anti-coagulant medication usage
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