Support for Depression Management in Adults

Antidepressant Adherence for Depressed Adults in Primary Care

Recruiting N/A Interventional Study
Depression
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
21 – 64
Sex
Any
Study type
Interventional
Purpose
Health Services Research
Participants needed
525 (estimated)
Sponsor
University of Pennsylvania · Other
Who this trial is looking for

This trial is looking for adults with depression to find better ways to manage their medication. Participants will receive help to stick to their prescribed antidepressant treatment and improve their mental health.

Are You a Good Fit for This Trial?

You may be able to join if

  • I am a patient at Penn Medicine primary care
  • I have been diagnosed with major depressive disorder
  • I have a score of 10 or higher on the PHQ-9 questionnaire
  • I am between 21 and 64 years old
  • I have been prescribed an antidepressant by my doctor
  • I am interested in taking my antidepressant medication
  • I own a cell phone
  • I can use an electronic pill bottle

You may not be able to join if

  • I have taken antidepressants in the past 90 days
  • I am pregnant or breastfeeding
  • I have an active substance use disorder other than nicotine
  • I have a history of treatment for bipolar disorder or schizophrenia
  • I was admitted to the hospital or visited the emergency department for suicidal symptoms in the past year
  • I cannot provide informed consent
  • I have been taking antidepressants for more than 10 days before starting the study

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.

Check Your Eligibility
About This Trial

The goal of this study is to test ways to help people improve their health and manage their medication for depression. This study will measure both medication adherence and depression outcomes.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Penn Medicine primary care outpatients * Clinical diagnosis of major depressive disorder * A score of 10+ on the Patient Health Questionnaire 9 (PHQ-9) * Age 21 to 64 years at the time of study entry * Prescribed an antidepressant by their primary care clinician * Express inte…
Contacts

Steven C Marcus, PhD

215-573-7941

marcuss@upenn.edu

CONTACT