No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
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Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 – 65
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
45 (estimated)
Sponsor
Case Western Reserve University · Other
Who this trial is looking for
This trial is looking for individuals aged 18 to 65 who have experienced sexual assault and are struggling with symptoms of depression or PTSD. Participants will take part in a one-session therapy and complete some assessments before and after treatment.
Are You a Good Fit for This Trial?
You may be able to join if
I am between 18 and 65 years old.
I have experienced unwanted sexual contact or sexual assault.
It has been at least 12 weeks and no more than 5 years since the event.
I live in Ohio.
I have at least moderate symptoms of PTSD or depression that have lasted for a month or longer.
You may not be able to join if
I have a current diagnosis of schizophrenia or a similar serious mental disorder.
I have bipolar disorder or severe depression that requires immediate treatment.
I have attempted suicide or engaged in severe self-harm in the past three months.
I am currently receiving cognitive behavioral therapy.
I do not clearly remember the event.
My medication for mental health has changed too much in the last three months.
I am in an ongoing relationship with the person who harmed me.
I have a current diagnosis of substance use disorder.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
The goal of this clinical trial is to test a brief, new psychotherapy (called Positive Processes and Transition to Health - Single Session, or PATH-SS) that aims to provide relief for people who are suffering after experiencing a sexual assault. This research will explore whether this new psychotherapy reduces sexual assault related distress, including posttraumatic stress and depression symptoms.…
The goal of this clinical trial is to test a brief, new psychotherapy (called Positive Processes and Transition to Health - Single Session, or PATH-SS) that aims to provide relief for people who are suffering after experiencing a sexual assault. This research will explore whether this new psychotherapy reduces sexual assault related distress, including posttraumatic stress and depression symptoms. The main questions it aims to answer are:
Does PATH-SS leads to improvements in PTSD and depression symptoms (pre- to post- and 1-month follow-up)? Do participants perceive PATH-SS to be acceptable, helpful, and do they complete/adhere to treatment? Participants will complete a pre-treatment/baseline assessment to confirm eligibility, and those who are eligible will receive the single-session intervention and will complete a post-treatment and a 1-month follow-up assessment of stressor-related symptoms.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
1. Age range: from 18 to 65.
2. Has experienced unwanted sexual contact or sexual assault with a minimum of 12 weeks since the event and a maximum of 5 years since the event.
3. Residence in the state of Ohio.
4. Elevated symptoms on either the Posttraumatic Diagnostic Scale (PD…
Inclusion Criteria:
1. Age range: from 18 to 65.
2. Has experienced unwanted sexual contact or sexual assault with a minimum of 12 weeks since the event and a maximum of 5 years since the event.
3. Residence in the state of Ohio.
4. Elevated symptoms on either the Posttraumatic Diagnostic Scale (PDS-5) or the Quick Inventory of Depressive Symptomatology (QIDS-SR), at least moderate: 18 on PDS-5 (Foa et al., 2016) and/or 11 on QIDS (moderate depression severity; Rush et al., 2003), with symptoms persisting for 1 month or longer.
Exclusion Criteria:
1. Current diagnosis of schizophrenia, delusional disorder, or organic mental disorder as defined by DSM-5.
2. Current diagnosis of bipolar disorder, depression with psychotic features, or depression severe enough to require immediate psychiatric treatment (i.e., serious suicide risk with intent and plan).
3. Severe self-injurious behavior or suicide attempt within the previous three months.
4. Currently engaged in cognitive behavioral psychotherapy.
5. No clear memory of the event.
6. Unstable dose of psychotropic medications in prior 3 months.
7. Ongoing intimate relationship with the perpetrator.
8. Current diagnosis of a substance use disorder (DSM-5).
9. Residence outside the state of Ohio.
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