Brain Stimulation for Major Depressive Disorder
Rapid Antidepressant Dynamics in Acute Neuromodulation Treatments
Recruiting
N/A
Interventional Study
Depression
Major Depressive Disorder
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 – 55
- Sex
- Any
- Study type
- Interventional
- Purpose
- Other
- Participants needed
- 200 (estimated)
- Sponsor
- Marta Peciña, MD PhD · Other
Who this trial is looking for
This trial is looking for adults with major depressive disorder who are not on any psychiatric medications. Participants will receive different types of brain stimulation and undergo brain scans to see how these treatments affect their mood.
Are You a Good Fit for This Trial?
You may be able to join if
- I am between 18 and 55 years old.
- I have been diagnosed with major depressive disorder.
- I am not currently taking any psychiatric medications.
You may not be able to join if
- I am pregnant or breastfeeding.
- I have a diagnosis of psychotic depression or bipolar disorder.
- I have had severe substance use in the last 2 months.
- I require immediate hospitalization.
- I have epilepsy or need anticonvulsant medication.
- I have received certain brain stimulation treatments in the last 2 months.
- I am currently receiving depression-specific therapy.
- I am actively suicidal or considered at high risk for suicide.
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
Check Your Eligibility
About This Trial
The goal of this clinical trial is to learn how different types of non-invasive brain stimulation affect mood and brain function in adults with major depressive disorder (MDD). It will also study how brain stimulation may work together with antidepressant treatments.
The main questions this study aims to answer are:
How do different patterns of brain stimulation affect mood in people with depres…
Trial Locations
Loading…
Loading trial locations…
Eligibility Criteria
Inclusion criteria:
1. Adults ages 18-55 (\~60% female).
2. Diagnosis of Major Depressive Disorder (MDD) with or without comorbid anxiety disorders (e.g., panic disorder) or Axis II disorders.
3. Psychotropic-free at enrollment.
Exclusion Criteria:
1. being pregnant or breastfeeding;
2. diagnosis…
Contacts