Neurofeedback to Treat Depression - 2

Recruiting N/A Interventional Study
Major Depressive Disorder (MDD)
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 – 65
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
80 (estimated)
Sponsor
University of Pennsylvania · Other
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About This Trial

This study tests the efficacy of a new psychotherapeutic strategy for reducing negative attention bias (and therefore depression severity) in participants with MDD. This real-time fMRI neurofeedback therapy uses cloud-based pattern classification to decode a patient's attentional state and dynamically modulate task stimuli (in a closed loop) based on this state.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Gender, inclusive * Adult aged 18 - 65 * Meets Diagnostic and Statistical Manual of Mental Disorders (DSM-5) criteria for MDD according to the Clinician-Administered MDD Scale for DSM-5 (unipolar depression or bipolar II depressed) * Scores at least a minimum score of 16 on Mo…
Contacts

Yvette Sheline, M.D.

(215) 746-2637

cndslab@pennmedicine.upenn.edu

CONTACT