11 Recruiting Trials

Clinical Trials
for COVID-19 in Louisiana

11 clinical trials for COVID-19 are currently recruiting participants at study sites in Louisiana. Study-related care is provided at no cost.

11
Recruiting trials
17
Study sites
5
Cities
7
Industry-sponsored
4
Phase 3

COVID-19 clinical trials in Louisiana: what to expect

COVID-19 research has shifted from the acute illness to its aftermath and its prevention. The most active area is long COVID: trials of antivirals, immune treatments and rehabilitation for fatigue, brain fog, breathlessness and rapid-heartbeat symptoms that persist months after infection. Vaccine trials test updated and next-generation vaccines, including nasal and combined flu-and-COVID shots. Treatment trials for people at high risk, and prevention studies for people with weakened immune systems, continue as well.

In Louisiana, recruiting covid-19 studies are concentrated in New Orleans, Baton Rouge, Shreveport and Lafayette, with sites in 1 other city. 7 of the 11 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who COVID-19 trials usually look for

Long COVID trials ask for symptoms that began after a confirmed or strongly suspected infection and have lasted at least three months, often with a particular symptom named. Acute treatment trials need a positive test within the past few days plus a risk factor such as age or a chronic condition. Vaccine trials specify an age group and your vaccination history, and most want people who are generally healthy. Many trials exclude pregnancy and a recent infection or vaccination.

What taking part involves

Long COVID trials run twelve to twenty-four weeks with questionnaires, sometimes exercise or breathing tests, and visits that can often be done by phone or video; many are placebo controlled. Vaccine trials involve one or two injections, a symptom diary for a week after each, a few blood draws and follow-up calls for a year or more. Acute treatment trials start the day you enroll, with swabs and check-ins for a few weeks. Study treatment and tests are free and visits are usually paid.

Questions worth asking the study team

How many visits must be in person; the chance of placebo; whether you can continue your current treatments; what counts as documentation of your original infection; and whether you will learn your own test results.

Showing 11 of 11 recruiting COVID-19 trials in Louisiana

A Clinical Study of Molnupiravir to Prevent Severe Illness From Coronavirus Disease 2019 (COVID-19) in People Who Are High Risk (MK-4482-023)
PHASE3 Cullman, Alabama +4 sites NCT06667700
This trial is looking for adults at high risk for severe illness from COVID-19. Participants will take the study drug molnupiravir or a placebo and monitor their health over time.
Recruiting
EPIC-Peds: A Study to Learn About the Study Medicine Called PF-07321332 (Nirmatrelvir)/Ritonavir in Patients Under 18 Years of Age With COVID-19 That Are Not Hospitalized But Are at Risk for Severe Disease
PHASE3 Phoenix, Arizona +4 sites NCT05261139
This trial is looking for young patients under 18 years old who have COVID-19 but are not hospitalized, and may be at risk for more severe illness. Participants will be given a medicine called nirmatrelvir/ritonavir to help treat their condition.
Recruiting
Study of a Recombinant Spike COVID-19 Vaccine With Matrix-M in Older Adults and People at Increased Risk of Severe COVID-19
PHASE4 Fair Oaks, California +4 sites NCT07861542
This trial is looking for older adults and younger individuals with health conditions that increase their risk of severe COVID-19. Participants will receive a single injection and have follow-up calls over three months.
Recruiting
Clinical Validation of the Aptitude Medical Systems Metrix COVID-19 Test
NA Baton Rouge, Louisiana +2 sites NCT06744660
This trial is looking for people who are at least 2 years old and have symptoms of a respiratory infection. Participants will provide swab samples for testing in a home-like environment.
Recruiting
Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia
PHASE3 New Orleans, Louisiana +4 sites NCT02735707
This trial is looking for adults in intensive care with severe community-acquired pneumonia. Participants will receive various treatments to see what helps them improve.
Recruiting
Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
N/A Phoenix, Arizona +4 sites NCT04278404
This trial is looking for children and young adults who are 21 years old or younger and are currently taking certain medications, or who have had a recent COVID-19 infection. They cannot be pregnant or have had certain recent medical procedures like dialysis, organ transplants, or other serious treatments. If you think your child might fit this description, it could be worth considering.
Recruiting
A Study to Investigate the Immunogenicity and Safety of mRNA COVID-19 Variant-containing Vaccine Formulations
PHASE4 Baton Rouge, Louisiana +4 sites NCT06585241
This trial is looking for adults who have been vaccinated against COVID-19. Participants will receive a new mRNA vaccine aimed at improving immunity to different variants of the virus.
Recruiting
Collection of SARS CoV-2 (COVID-19) Virus Secretions and Serum for Countermeasure Development
N/A New Orleans, Louisiana +1 sites NCT04956445
This trial is looking for patients who have tested positive for COVID-19 or other respiratory viruses. Participation involves providing samples of your blood and respiratory secretions to help understand COVID-19 infections and their effects.
Recruiting
Efficacy and Safety of Tozorakimab in Patients Hospitalised for Viral Lung Infection Requiring Supplemental Oxygen
PHASE3 Birmingham, Alabama +4 sites NCT05624450
This trial is looking for adults who are hospitalized with a viral lung infection and need extra oxygen. Participants will receive treatment with tozorakimab along with their usual care to see if it helps prevent worsening conditions.
Recruiting
Intervention to Prevent Behavioral Health Symptoms Among Pandemic Affected Children
NA New Orleans, Louisiana +4 sites NCT05639465
This trial is looking for children who experienced the COVID-19 pandemic and a major disaster. Participants will be part of a program aimed at preventing mental health and behavioral issues.
Recruiting
SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
N/A Birmingham, Alabama +4 sites NCT03452774
This trial is looking for cancer patients to see if an AI tool can help match them to clinical trials. Patients will have their cancer-related biomarkers evaluated to find suitable studies for their condition.
Recruiting

Where the COVID-19 studies are in Louisiana

  • Barnum Medical Research ( Site 3828), Natchitoches1 trial
  • Coalition for Compassionate Schools, New Orleans1 trial
  • Communities in Schools Gulf South, New Orleans1 trial
  • Louisiana State University Health Sciences Shreveport, Shreveport1 trial
  • Massive Bio SYNERGY-AI site, New Orleans1 trial
  • Ochsner Baptist Clinical Trials Unit, New Orleans1 trial

Counts are recruiting studies listing at least one site in Louisiana, from ClinicalTrials.gov, refreshed every two days.

COVID-19 clinical trials in Louisiana: common questions

How many COVID-19 clinical trials are recruiting in Louisiana?
TrialFinder currently lists 11 recruiting COVID-19 clinical trials with study sites in Louisiana. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are COVID-19 clinical trials located in Louisiana?
Study sites for the COVID-19 trials listed on this page include Baton Rouge, New Orleans. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a COVID-19 clinical trial in Louisiana?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many COVID-19 trials in Louisiana also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a COVID-19 clinical trial in Louisiana?
Each study sets its own criteria based on age, COVID-19 diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Are there clinical trials for long COVID?
Yes, and they are among the most active COVID trials. Most require symptoms that have lasted three months or more after an infection and name the symptom they study, such as fatigue, brain fog or breathlessness.
Can I join a COVID vaccine trial if I am already vaccinated?
Usually yes. Most current vaccine trials test updated or next-generation vaccines in people who have been vaccinated before, and ask about the date of your last dose.
Do I need a positive test to join a COVID treatment trial?
For acute treatment, yes, within the last few days. Long COVID trials accept a past positive test or a documented clinical diagnosis, and some accept a strongly suspected infection.
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COVID-19 trials study antiviral agents, monoclonal antibodies, long-COVID interventions, and vaccine platforms for prevention and treatment of SARS-CoV-2 infection.

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